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Are you pts using cannabis?
In Canada - 20% reported using w/in past 2 years
Use for pain, sleep, anxiety
78% noted effi

Eric Dein ericdeinmd

1 year 10 months ago
Are you pts using cannabis? In Canada - 20% reported using w/in past 2 years Use for pain, sleep, anxiety 78% noted efficacy Compare to another study said 57% stopped due to inefficacy, 28% AEs - very diff result 70% did not tell their doc 16S18 @BharatKumarMD #ACR24 @RheumNow https://t.co/6NAECW5MJK
Serrano-Combarro et al. Baricitinib in RA-ILD . 72 patient case series. PFTs in picture. HRCT stable/improved in 72% ove

Richard Conway RichardPAConway

1 year 10 months ago
Serrano-Combarro et al. Baricitinib in RA-ILD . 72 patient case series. PFTs in picture. HRCT stable/improved in 72% over 24 months. Dyspnoea stable/improved in 90%. @RheumNow #ACR24 Abstr#0476 https://t.co/aVI2kRZkMN https://t.co/4l5GKsFKtm
Medical cannabis in the USA today
Variation in state practice on recreational/medical/decriminalization
16S18 @BharatKum

Eric Dein ericdeinmd

1 year 10 months ago
Medical cannabis in the USA today Variation in state practice on recreational/medical/decriminalization 16S18 @BharatKumarMD #ACR24 @RheumNow https://t.co/9Ex3lge6KO
PRO-SPIRIT trial data on 1192 PsA pts showed IL-17Ai seemed better than IL-12/23i and IL-23i improving cDAPSA at 3m and

Adela Castro AdelaCastro222

1 year 10 months ago
PRO-SPIRIT trial data on 1192 PsA pts showed IL-17Ai seemed better than IL-12/23i and IL-23i improving cDAPSA at 3m and as effective as TNFi and JAKi. No much differences seen at 12m. Abst#0076 #ACR24 @RheumNow https://t.co/dScwsmkDOe
In the SPACE cohort, patients with chronic back pain suspected of axial spondyloarthritis often receive a diagnosis with

Antoni Chan MD (Prof) synovialjoints

1 year 10 months ago
In the SPACE cohort, patients with chronic back pain suspected of axial spondyloarthritis often receive a diagnosis within 35 months from symptom onset. Key determinants for early diagnosis include HLA-B27 positivity and sacroiliitis on imaging. Early diagnosis can be a game… https://t.co/RrcrtRoMfL
#0584🔬Real-World PsA Study:Tofacitinib

➡️141 pts:47% mono,53% combo;~70% on Rx @ 6mo

➡️Similar ⬆️in di

Caoilfhionn Connolly CaoilfhionnMD

1 year 10 months ago
#0584🔬Real-World PsA Study:Tofacitinib ➡️141 pts:47% mono,53% combo;~70% on Rx @ 6mo ➡️Similar ⬆️in disease outcomes (cDAPSA LDA: 31% mono vs 21% combo; MDA ~16%). ➡️No significant differences mono v combo outcomes 🩺Tofa effective in diverse PsA population #ACR24 @RheumNow
With many treatments for #PsA and #PsO, what are the prescribing trends?

Abstract 0604: TNF inhibitors remain the most

Akhil Sood MD AkhilSoodMD

1 year 10 months ago
With many treatments for #PsA and #PsO, what are the prescribing trends? Abstract 0604: TNF inhibitors remain the most common (~60%), but over the past 10 years, IL-17i use rose from 0.2% to 19%, and IL-23i from 0.1% to 39.7%! #ACR24 @RheumNow https://t.co/4TnCAkHfuY
Cannabis and Physical Function
Very small effects on meta-analysis

PO cannabis - 4% benefit (0.1-8%) of achieving at le

Eric Dein ericdeinmd

1 year 10 months ago
Cannabis and Physical Function Very small effects on meta-analysis PO cannabis - 4% benefit (0.1-8%) of achieving at least MID of SF36 function scale 16S18 @BharatKumarMD #ACR24 @RheumNow https://t.co/qQOYt1m3ub
For many years glucocorticoids were the mainstay of our treatment of granulomatosis with polyangiitis (GPA). The paradigm shifted with cyclophosphamide and then again with rituximab, and we used less steroids, but we still used lots. Avacopan teased the demise of steroids, but in the trial they, and now we, still use them. Glucocorticoids are our old trusty friend, our comfort blanket. But no more! Good riddance to the medication with the
Can multidisciplinary clinics improve quality of care for PsA?
Abstract 0596: Multidisciplinary care in PsA associated

Akhil Sood MD AkhilSoodMD

1 year 10 months ago
Can multidisciplinary clinics improve quality of care for PsA? Abstract 0596: Multidisciplinary care in PsA associated with ↓ time to first biologic, ↑ dermatology & nurse visits, and better CV risk assessment. #ACR24 @RheumNow https://t.co/2OnUR6te63
Pharmacologics:
Cannabis absorption and metabolism is variable
Inhaled absorption 10-35%
THC is 97% protein bound, lipo

Eric Dein ericdeinmd

1 year 10 months ago
Pharmacologics: Cannabis absorption and metabolism is variable Inhaled absorption 10-35% THC is 97% protein bound, lipophilic and deposits in fat and spleen Liver function is critical for THC metabolism 16S18 @BharatKumarMD #ACR24 @RheumNow
Quinn @KQuinnRheum @petercgrayson et al. FDG-PET is not particularly useful in monitoring GCA on tocilizumab. Toc reduce

Richard Conway RichardPAConway

1 year 10 months ago
Quinn @KQuinnRheum @petercgrayson et al. FDG-PET is not particularly useful in monitoring GCA on tocilizumab. Toc reduces but often not eliminate PET inflammation. PET activity does not predict relapse or vascular progression @RheumNow #ACR24 Abstr#0742 https://t.co/1qcJCGV118 https://t.co/6mBCgcbYo6
Prevalence of HLH among pts w/SLE: lower than consults would suggest!

Observational study using NIS: 139 cases out of

Mike Putman EBRheum

1 year 10 months ago
Prevalence of HLH among pts w/SLE: lower than consults would suggest! Observational study using NIS: 139 cases out of >100k pts w/SLE (0.13%); 6 fold increase in mortality Fits my priors; HLH is overdiagnosed, but bad when it happens @RheumNow #ACR24 Abstr#0619 https://t.co/iz3BlUOJb9
#Abstract0649
Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing inc

Akhil Sood MD AkhilSoodMD

1 year 10 months ago
#Abstract0649 Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing incident LN from SLE, treated LN & healthy controls. @RheumNow #ACR24 https://t.co/aCRzt9TtoK
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