Dr. John Cush RheumNow
2 years 2 months ago
DBRPCT of Krill oil (4 g/d;KOC) vs PBO in 78 #SLE pts for 24 wks. KOC Rx pts had signif increase in Omega-3 Index 4.3% to 7.17% (4wks) to 8.05% (24wks) w/ no change SLEDAI-2K. But 9pts w/ hi activity (SLEDAI≥9) showed signif Dz activity improvements https://t.co/ODLqqZzGQx https://t.co/tehHk4MhbZ
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Location matters; Geo-rheumatology?
A secondary analysis of the PEXIVAS study showed antineutrophil cytoplasmic antibody–associated vasculitis (AAV) patients complicated by diffuse alveolar hemorrhage (DAH) may have improved with plasma exchange and glucocorticoids, the results did not achieve significance.
Dr. John Cush RheumNow
2 years 2 months ago
Patients with Financial Limits Struggle with Medication Adherence
The National Health Interview Survey reveals that nearly 1 in 5 patients with rheumatologic disease in the U.S. face economic challenges, including food insecurity and CRM nonadherence.
https://t.co/DhiLDq3fjZ https://t.co/zqQRAJDrzc
Dr. John Cush RheumNow
2 years 2 months ago
Bad News Coronary Artery Calcium in Rheumatic Patients
In the 2024 SCCT meeting, Dr. Brittany Weber presented findings showing that incidentally discovered CAC in patients with IMID can lead to worse outcomes, even without prior ASCVD.
https://t.co/aJhf0IL1WW https://t.co/uMl89rXjBK
Dr. John Cush RheumNow
2 years 2 months ago
Earlier RA Diagnosis Leads to Lower Costs of Care
A study from the Leiden Early Arthritis Clinic shows that is RA is diagnosed within 12 weeks after symptom onset, treatment costs were lower in both autoantibody-negative and autoantibody-positive RA.
https://t.co/TnrpZGZ4fX https://t.co/elNQ3Pde2a
Dr. John Cush RheumNow
2 years 2 months ago
CDC warns of Listeria outbreak assoc w/ deli meats - in 12 US states (lead by NY, and MN, MO, IL, WI, PA, VA, GA, NJ, DE, MD, MA, NC), 28 cases, 28 hospitalized, 2 deaths. @risk are the pregnant, elderly, immunosuppressed. Cook deli meats >165F https://t.co/SWKMhIBQEi https://t.co/snLjBKn1UJ
Dr. John Cush RheumNow
2 years 2 months ago
Cross-sectional study of 154 adult DLE pts in the Philadelphia area assessed DLE Dz severity (by CLASI) & geoghraphic distribution to ID area deprivation (ADI). ADI > 5 (geospatial disadvantaged) was assoc w/ signif (4X) higher risk of mod-Severe Damage https://t.co/dgeGwzNTKm https://t.co/B3hmUE1G9U
Dr. John Cush RheumNow
2 years 2 months ago
2001-2004 NHANES population study shows 28% report hx of erectile dysfunction (ED) & 19% w/ arthritis. Having arthritis was assoc w/ 4 fold higher ED risk; mostly in #OA (OR=1.11), RA (OR=1.03). https://t.co/L2LhEPH9DY https://t.co/yLhVmLw7nt
Dr. John Cush RheumNow
2 years 2 months ago
Drug Safety Update, from UK MHRA, shows impt interaction between tramadol and warfarin. Tramadol may increase the INR with risk of major bruising and bleeding when warfarin and tramadol are taken concomitantly. https://t.co/mgmeMJzdLa
There are numerous impediments to diagnosis or referral; and a new study evaluates patient use of a mobile artificial intelligence (AI)–based symptom checker for diagnoses, but demonstrated only modest accuracy when applied to a cohort of patients with joint symptoms.
Dr. John Cush RheumNow
2 years 2 months ago
Inpatient study 5495 Adult Stills Dz (AOSD) hospitalizations (2016–2019). Pts w/ HLH (6.2%) had higher mortality (9% vs 1.5%). Deatjs Independent predictors: DIC (OR 6.1), liver failure (7.2), Infx (3.7), resp failure (6.9),thrombotic microangiopathy (14) https://t.co/BQsbVnw2Ir https://t.co/mbn9JuN7ow
Researchers at Rush University analyzed clinic MDHAQ data and found between 36-40% of osteoarthritis and rheumatoid arthritis patients screen positive comorbid anxiety, depression, or fibromyalgia.
Dr. John Cush RheumNow
2 years 2 months ago
UK Natl Early Inflammatory Arthritis Audit (5/18-10/22) compared 682 persistently active vs 1026 low activity RA pts. pactiveRA were younger, more women. pactiveRA assoc. w/ Age, gender, smoking, depression, lung dz, gastric ulcers, baseline steroids https://t.co/QGuUZmSBHD https://t.co/TDlPFmTQEn
