2 large 48-wk phase 3 trials (Be HEARD I/II) of Bimekizumab vs PBO in moderate-to-severe hidradenitis suppurativa shows BKZ to be safe & significantly effective (48% vs 29% & 52% vs 32%) vs PBO. https://t.co/qJykCPMn4U https://t.co/zVOTxLkW9R https://t.co/3I4eOfPYWk

• Efficacy and safety of bimekizumab in patients with moderate-to-severe hidraden…
• https://buff.ly/3R7FZIn

No Great Options for Treating VEXAS For patients w/ VEXAS, treatment decisions are unfortunately fraught with tradeoffs between effectiveness and risk of adverse effects, a French registry study showed. https://t.co/xCQYHwgUH9 https://t.co/N5Q03izr8u https://t.co/csIixQO3sJ

• No Great Options for Treating VEXAS | RheumNow
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Biologic-treated Psoriasis has Less Progression to Psoriatic Arthritis A single center study demonstrates that biologic treatment of PsO significantly reduces the likelihood of PsA development; suggesting a role for more aggressive treatment of PsO. https://t.co/VHk2KEsP8d https://t.co/1r4zVAzrMw

• Biologic-treated Psoriasis has Less Progression to Psoriatic Arthritis | RheumN…

ACR Website to Support PCPs The American College of Rheumatology recently launched Rheumatology for Primary Care, a new resource for PCP and APP offering them expanded support and guidance to identify rheumatic diseases in their patients. https://t.co/yZbpG3598O https://t.co/S4oYNMrdqt

• ACR Website to Support Primary Care Practitioners | RheumNow

Colchicine prophylaxis w/ allopurinol (“start-low go-slow” 100mg escalation strategy), is best used in pts w/ gout flare in month prior to allopurinol. Longer prophylaxis may be required w/ ongoing flares in 1st 6mos of allopurinol if T2T not achieved https://t.co/qWUwrAcCJZ https://t.co/6S7Y6p7BnF

• Predicting gout flares in people starting allopurinol using the start‐low go‐sl…

Ramosetron,a 5-HT3 recept antagonist used for post-op N/V,t has been used for adjunctive pain Rx & IBS. An 80 FM pt DBRCT tested PBO vs Ramosetron (.3 mg/day IV x5d). @d5 had signif better VAS pain (1.18  vs 0.54, p< 0.05), but didnt persist till day 28 https://t.co/0ABduv8Nlq https://t.co/WGlxIhst1o

• Ramosetron as an add-on therapy for refractory fibromyalgia: A randomized, doub…

Anakinra in COVID showed mixed (often negative) results. But this Turkish retrospective observational study comparing standard of care to IV anakinra in severe COVID pts. IV ANAK had less thromboembolic event (5% vs 12.3%, p = 0.038), better survival https://t.co/4webWJKEfB https://t.co/85GnCd6N8O

• Intravenous high-dose anakinra drops venous thrombosis and acute coronary syndr…

Forbes on the future of CAR-T cell therapy - A Gamechanger For Autoimmune Diseases. Innovation, costs, more trials and regulatory differences for autoimmune (vs cancer) patietns? https://t.co/1Yg40HPTzh https://t.co/NqCwEzmZ1g

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There's a huge difference between knowing the name of something and knowing something. We talk in fact-deficient, obfuscating generalities to cover up our lack of understanding.

#JuneIssue | Relapsing polychondritis is challenging to diagnosis owing to overlapping symptoms with other conditions Learn more about the clinical features and differential diagnoses in this #Review https://t.co/iXl9rQ0ONS

• Relapsing polychondritis: clinical updates and new differential diagnoses

Kaiser/California EHR study of #SLE pregnancies (2011-2020) - 657 pregnancies in 453 prs; The live birth rate = 74%, 23% w/ Spontaneous Ab, 2% ectopic/molar & <1% stillbirths. Variable outcomes by race & ethnicity, aPL status & nephritis history https://t.co/gvmYpTuFon https://t.co/9TeG8kfLmK

• Pregnancy Outcomes in a Diverse US Lupus Cohort

JAMA full read comprehensive review of 'Chronic Pruritus' affecting 22%, 1% of all out pt visits - Dx algorithm - Pathophys - Rx options - Alternative Rx https://t.co/4sd2HqUX9Y https://t.co/FoVHFnfEPa

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