Dr. John Cush RheumNow
2 years 4 months ago
JAMA: SLE Review
Drs.Siegel & Sammaritano (from HSS in NYC) published an impressive overview of SLE) in JAMA. This timely, well-written review covers the many complexities of this multi-organ disorder that affects nearly 3.4 million people worldwide.
https://t.co/H9M3KPDkhf https://t.co/WBMjKZzziX
Dr. John Cush RheumNow
2 years 4 months ago
BASDAI tends to be higher in women while there is no appreciable difference in ASDAS scoring in men compared to women.
Dr. L. Eder believes this could be due to the pain scoring in both indices.
#RNL2024 @RheumNow @lihi_eder https://t.co/PSnFwX3eHu
Dr. Eder delivered an illuminating talk at RheumNow Live 2024 on sex differences in psoriatic arthritis; the disease may manifest differently in men and women, and therapeutic responses may differ between the sexes.
chaim putterman ChaimPutterman
2 years 4 months ago
Is IL-6 a potential therapeutic target in neuropsychiatric lupus (NPSLE)?
Just published in the Journal of Neuroinflammation- Some interesting findings from the Putterman lab in a murine NPSLE model... https://t.co/7yn2o7ZRxS
Dr. John Cush RheumNow
2 years 4 months ago
In RA, previously affected Jts more likely to flare ("joint-specific memory") ?mediated by synovial resident memory T cells, predominantly CD8+ T cells, with a restricted TCR repertoire, responding to specific Ags by releasing chemokines & cytokines https://t.co/VfFZ03yZYL https://t.co/npX3TGDe5A
Dr. John Cush RheumNow
2 years 4 months ago
Cross-sectional study of7887 NY & IL nurses: between 2018-21 top reasons for 2287 leaving nursing were planned retiring (39%), burnout (26%), insufficient staffing (21%), family obligations (18%) & COVID (17%)-- all addressable by health care employers https://t.co/Ls6p060mFB https://t.co/Pxpa8fqchz
Anti–melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) is a rare, aggressive and progressive subtype of DM. Its' severity is dependent on the development of progressive interstitial lung disease (ILD), manifesting as either rapidly progressive ILD (RPILD) and chronic ILD (CILD).
Bone and musculoskeletal disease researchers and physicians from around the world will meet today in London, UK for the opening of the largest scientific event in the field, the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2024).
The management and outcomes of neuropsychiatric systemic lupus erythematosus (NPSLE) can be challenging as there is limited data. A retrospective cohort study identified 350 NPSLE events (between 1999-2015) defined by ACR definitions and categorized as being: central/diffuse, central/focal and peripheral. Clinical outcomes and predictors of clinical improvement/resolution were investigated.
Imaging is often instrumental in diagnosing and staging patients diagnosed with giant cell arteritis (GCA).
Dr. John Cush RheumNow
2 years 4 months ago
Seasonal Pathogens and Henoch-Schönlein Purpura
Epidemiologic studies of Henoch-Schönlein purpura (HSP) have suggested seasonal variation in occurrence rates (higher from September-April, lower in June-August), suggesting a role for infectious triggers.
https://t.co/MmuVVziqv8 https://t.co/PhidOFTbFV
Dr. John Cush RheumNow
2 years 4 months ago
Pearl: Patients with persistent TMJ pain are more likely to have fibromyalgia than inflammatory or degenerative arthritis (as the underlying cause of their chronic pain) https://t.co/gCEm8A3RAT https://t.co/bvK2ii4fXP
Dr. John Cush RheumNow
2 years 4 months ago
IL-1 recept accessory protein (IL1RAP) shown to block mediators (IL-1, IL33, IL36) that may drive systemic sclerosis. In vitro, IL1RAP inhibited fibroblasts and endothelial cells; in mouse models of SSc anti-IL1RAP decr dermal & pulmonary fibrosis. https://t.co/jWjUMKdqGw https://t.co/O3o5iDHD6X
