EGPA - Peanut butter and Jelly @philseo Respiratory symptoms and systemic disease Respiratory: non-systemic (inhalers, steroids, irrigation) IL-5 inhibs Non-respiratory: eosinophilic (myocarditis, urticaria, EE), vasculitis (MM, GN, DAH, purpura, arthralgias) #RNL2024 @RheumNow https://t.co/KTlvZ1cnfH

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"EGPA is a lot like peanut butter and jelly, two separate things showing up at the same time (in terms of respiratory and systemic manifestations.)" Dr. @philseo at #RNL2024 @RheumNow https://t.co/l0WgG1caN0

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“Patients with EGPA are like peanut butter and jelly … 2 different manifestations: respiratory manifestations and systemic manifestations” - Dr. P Seo with lunch on his mind. #RNL2024 @rheumnow https://t.co/y7SLEG9qRt

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Dr. P Seo's Pearls for #Vasculitis: 1. Weekly or q2weeks SC TCZ is fine for newly diagnosed patients, but if pts relapse, use weekly TCZ. 2. oral steroids perform fine (no need to do IV pulse) even in pts with vision changes 3. taper steroids over 3-4 months @rheumnow #RNL2024

The great unknown with tocilizumab in GCA, do you stop, how do you stop, etc. @philseo approach. I'm not as brave! Usually park at every other week dosing @RheumNow #RNL2024 https://t.co/y7mg57mWND

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Do you have GCA patients on low dose prednisone? Feel reassured. Dr. @philseo provides data showing that low dose prednisone may be helpful in remission maintenance. #RNL2024 @RheumNow https://t.co/oyOsczfkfv

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Interesting nuance from @philseo re tocilizumab in GCA. For new onset disease, it may be appropriate to use every other week tocilizumab @RheumNow #RNL2024 https://t.co/moCvpQSkq0

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Do you need to pulse steroids in GCA? ACR 2022 abstract#0459 data says oral only may be sufficient Oral vs IV MP - p=0.621 Still favor IV in severe cases @philseo #RNL2024 @RheumNow

Amaurosis fugax is not the only vision symptoms to assess in patients with #GCA. Blue vision, double vision (if patients have to look at you in a side gaze prevent double vision) may also be present - Dr. P Seo @rheumnow #RNL2024 https://t.co/AhQnOJF7fa

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#RNL2024 @RheumNow @philseo: I now give Tociliizumab for nearly all patients with GCA GiACTA shows we weren't doing well enough with steroid monotherapy GiACTA shows dosing frequency does not make a big difference in new diagnosis, but makes a difference in relapsing disease https://t.co/JBgUQtZSAr

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When thinking of GCA there are only 2 questions you need to ask. Dr. @philseo reminds us to 1. Establish if new or recurrent disease 2. Assess for presence of visual symptoms #RNL2024 @RheumNow https://t.co/MGML3EafPu

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How I do it, treatment of CGA with Dr. @philseo, who thoughtfully paused so everyone could take a picture of this slide knowing full well it was already at our fingertips! Such a gentleman! #RNL2024 @RheumNow https://t.co/8kqacqkRM6

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Dr. Phillip Seo contemplates if Taylor and Travis had vasculitis, surely the dose for each would not be the same. Wish you were here @rheum_cat to weigh in on this. #RNL2024 @rheumnow https://t.co/1ynctgIknx

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In case you needed any more reasons why @philseo is the best @rheum_cat , this is his first slide @RheumNow #RNL2024 https://t.co/Ar0v7sQuuX

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Dr @anisha_dua's takehome points for treating GPA in 2024 *RTX and CYC are both effective followed by RTX at least 500mg q 6 mo for at least 2 years *PLEX not generally used, but may be effective in preventing ESKD *Rapid GC tapering may not be suitable for all pts *Avacopan is… https://t.co/haI19Sgpmu https://t.co/jhjXLwd0Uw

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