Dr. John Cush RheumNow
2 years 9 months ago
Study from British Columbia, Canada, showed between 2010 & 2020, they saw 31% more new pt rheum consults (149,902); 1st time consults for inflammatory arthritis incr 28% to 51%. While time to 1st visit decr. 35%, time to DMARD initiation was unchanged https://t.co/Et7GzxKeNe https://t.co/2as2YuIV4d
Psoriatic arthritis and the gut microbiome have become more intertwined, especially in the past few years. It was to my amazement that one of the first abstracts I came across was the effect of probiotic modulation on gut dysbiosis and disease activity in psoriatic arthritis patients.
Dr. John Cush RheumNow
2 years 9 months ago
Watch: Effects of Apremilast on Cardiometabolic Effects in PsA
https://t.co/aKMxEfbc4c https://t.co/wjcEjLtlaC
While adult rheumatology programs continue to have high match rates, pediatric rheumatology programs remain less popular.The National Residency Matching Program announced yesterday that the 2024 rheumatology fellowship match filled 97.6% (124/127) of programs, and 98.9% (273/276) of rheumatology fellowship positions. This is on par with last years (2023) adult rheumatology match wherein 97.8% (265/271) of the rheumatology fellow positions were
The Lancet Rheumatology TheLancetRheum
2 years 9 months ago
NEW Health Policy—Diagnosis and investigation of suspected haemophagocytic lymphohistiocytosis in adults: 2023 Hyperinflammation and HLH Across Speciality Collaboration (HiHASC) consensus guideline https://t.co/WYNcVigb7n Free to read with registration on https://t.co/28wkm59DgB https://t.co/Qbm1y76o3E
Dr. John Cush RheumNow
2 years 9 months ago
Real World Experience with PEXIVAS Low Steroid Taper
Dr. Mike Putman discusses abstract 0725 with Dr. Sophie Nagle at the 2023 ACR Convergence meeting in San Diego, CA.
https://t.co/lXTyb93ata https://t.co/kC6J9Zuurf
Dr. John Cush RheumNow
2 years 9 months ago
What do you think of the concept of "dysuricemia" - the concept that both hyperuricemia and hypouricemia influence diseases. “The lower, the better” is incorrect; the ideal is to maintain normouricemia, or optimal SU level, to reduce the urate burden https://t.co/Vi9htWTNwr https://t.co/fsx9Oq08Ak
Dr. John Cush RheumNow
2 years 9 months ago
Reconsidering Steroids
Not one of us in rheumatology hasn’t prescribed steroids, but we need to reconsider how much/how often we use them. In almost every disease state we treat, we are seeing progression towards lesser and shorter courses .
https://t.co/VRlCeNXyKR https://t.co/k5Uy7IHr3h
Dr. John Cush RheumNow
2 years 9 months ago
TNFi and RA-ILD – The Pendulum Swings Again
Tumour necrosis factor inhibitors (TNFi) revolutionised the treatment of rheumatoid arthritis. They heralded the wave of advanced therapies, which has transformed the treatment landscape in rheumatic disease.
https://t.co/zBwJKyDihL https://t.co/uCLnmaLC9j
Dr. John Cush RheumNow
2 years 9 months ago
Single center obs. study 74 RA-ILD pts Rx w/ antifibrotics (40 nintedanib; 34 pirfenidone); F/U 89 wks, had signif improvement in FVC estimated decline after antifibrotics (-0.3% w/ vs -6.2% w/o). 35% died, 4 lung transplants. 55% AEs, 46% D/C Rx https://t.co/s6O5uU3z2i
Dr. John Cush RheumNow
2 years 9 months ago
#ACR23 Abst#1629 from FORWARD registry showed RA pts (n667) with LONG COVID (15%) had worse RA pre-COVID and post-infx, and had worse COVID (more ABx & hospitalization). RA-long Covid pts had 3fold more fibromyalgia (13 vs 41%) https://t.co/VFNAnSxNzN https://t.co/WLqmdM3Nn2
Dr. John Cush RheumNow
2 years 9 months ago
Watch: No Increased Mortality in Patients with RA Receiving Checkpoint Inhibitors
Dr. Mike Putman discusses abstract 1071 with Dr. Madeline O'Sullivan at the 2023 ACR Convergence meeting in San Diego, CA.
https://t.co/YdIlhLf5gh https://t.co/6dfWHakboh
Dr. John Cush RheumNow
2 years 9 months ago
ACR Daily Recap - MONDAY
Panelists: Drs. Kathryn Dao, Michael Putman and Eric Dein
Moderator: Dr. Jack Cush
https://t.co/b1k1gsHI2z https://t.co/BWu7GXFxhj
Dr. John Cush RheumNow
2 years 9 months ago
IgG4 disease- the WInS withdrawal study results
https://t.co/rg0YJ0LlZM https://t.co/L6SzcD7QlJ
It has been just over a decade since the approval of tofacitinib (JAK1/JAK3-inhibitor) by the US FDA for the treatment of rheumatoid arthritis. Since then, baricitinib (JAK1/JAK2-i), filgotinib and upadacitinib (both selectively targeting JAK1) also have been licensed for the treatment of rheumatoid arthritis. As there are many more JAK-inhibitors evaluated in clinical trials currently, how do you stand out?

