#IA Injection in #knee #OA. TLC599 vs #dexamethasone vs saline #RCT-blinded. Both active #Rx better than #PBO. Some differences in average daily pain between active drugs. Not sure where it may fit in? After IA steroid failure? L18 #ACR23 ⁦@ACRheum⁩ ⁦@RheumNow⁩ https://t.co/rLh6ISBpUw

Inflammation in interstitial fibrosis & tubular atrophy (i-IFTA) is assoc w/ GFR loss accdg to this study by Dr SMalvica et al. ✳️In pts w/ mod-to-severe IFTA, the degree of i-IFTA was assoc'd with higher risk of GFR loss #ACR23 ABST2552 @RheumNow https://t.co/7iA0nzbmgM

Bastard et al. 12,071 French PsA. Low incidence serious infections on advanced therapy - 17 per 1,000 person-years. Significantly lower risk ETN (HR 0.70), UST (HR 0.56) vs ADA. Others similar. Abstr#2566 #ACR23 @RheumNow https://t.co/GGDvRxP9ht https://t.co/Ol7G1OG73t

Interesting look into autoantibody profile of rheumatic disease-ILD compared to IPF Identified 7 ab in RD-ILD, emphasizing lack of autoimmunity in IPF Different mechanisms of damage and progression based on ab profile? @RheumNow #ACR23 Abs#2572 https://t.co/5rtXnOe9oJ

#ACR23 Abstr#2578 AI to phenotype sporadic IBM vs AI Myositis -Anti-NT5c1A assoc with dysphagia -Anti-Ro52/TRIM21: female -Anti-VCP: male -Anti-NT5c1A + clinical markers: high accuracy in separating SIBM vs AIM Need longitudinal data for clusters to be meaningful @RheumNow https://t.co/fu0a074XAZ

Beware of the « HOT stuff 🌶️ bias » In his very didactic catalogue of bias, Timothy McAlindon particularly warns us against the hot stuff, or the tendency to be less rigorous in the scientific approach when a topic is fashionable @RheumNow #ACR23 https://t.co/rS8lItDrGS

#ACR23 Abstr#2580 Could high-intensity resistance training improve outcomes in myositis? RCT showed 16 wks of training was tolerable, improved quality of life & functional capacity, without increasing disease activity/damage @RheumNow https://t.co/O1nP2x9C1L

#ACR23 BEST Abstracts from San Diego – Day 1 From hundreds of online presentations, the poster floor and the plenary podium, here are some of the best abstracts from 11/12/23. You can spot these on Twitter by looking for the (#ACRbest) hashtag. https://t.co/h4RvFy66z9 https://t.co/LEhAUaw6Cj

• #ACR BEST Abstracts from San Diego – Day 1 | RheumNow

Do Probiotics Improve PsA? Probiotics and gut microbiome is a hot topic in the research world and amongst patients. Often, one the questions I get after sharing the diagnosis of PsA is, “Is there anything I can eat/not eat to make this better?” #ACR23 https://t.co/aK56UXz3gs https://t.co/p2AuzcWyq9

• Do Probiotics Improve Psoriatic Arthritis? | RheumNow

Who gives a ‘JAK’ why and how they work, as long as they do! Several abstracts have studied the mechanism of action of JAKi in various diseases. JAKi alter many other mediators affected by the JAK STAT pathway. #ACR23 https://t.co/xqQF8SULgp https://t.co/DZtEly8GEq

• Who gives a ‘JAK’ why and how they work, as long as they do! | RheumNow

RHEUM Survey Question: Your choice of a biologic in patients with SpA is mostly influenced by? CLICK here to answer: https://t.co/afJmqzzPYi

• SPONDYLOARTHRITIS (SpA) PATIENTS (PsA, AS, and nr-axSpA) | RheumNow

Will CAR T Cells also treat RA? Dr. Jonathan Kay reports on abstract 0424 from #ACR23. https://t.co/XvNMXAFkWe https://t.co/HVvBLhqe8H

• Will CAR T Cells also treat RA? | RheumNow

#ACR23 Daily Recap Panel - Day 1 Join our live stream panel discussion as we dive deep into the highlights and key takeaways from day one of ACR 2023. https://t.co/hApuycYzD2 https://t.co/1CD3rLLV7D

• ACR 2023 Daily Recap Panel - Day 1 | RheumNow