Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have transformed cardiometabolic medicine and are now attracting intense interest in inflammatory disorders.
Dr. John Cush RheumNow
3 months ago
True or False: Low-dose aspirin given at giant cell arteritis diagnosis is associated with a lower risk of major adverse cardiovascular events. Put your answer to the test in the latest RheumIQ quiz at https://t.co/XLPVoyCbLB. https://t.co/C5CSwuv5mF
The future of avacopan is up in the air. In April, the FDA issued a drug safety warning, previously requesting that Amgen to pull its rare disease drug Tavneos from the market. Now, there appears more pressure to remove it from the market.The FDA’s concern is that the data, orginally generated by Chemocentryx, was "manipulated" during the FDA submission.
Dr. John Cush RheumNow
3 months ago
Study of 216 RA pts - Serum IL-8 independently assoc w/ RA Dz activity. CRP & IL-6 significantly associated w/ higher IL-8 levels, but RF & CCP did not. IL-8 also correlated w/ CV risk (SCORE2) & carotid intima media thickness https://t.co/aqUoAeXFFP https://t.co/ZW7OAx8YGK
Dr. John Cush RheumNow
3 months ago
Dental study from India assessed periodontal Dz (PD) in 170 RA vs 170 non-RA pts. RA had more PD, ^ESR, more mild PD (39% v 29%). DAS-28 correlated w/ PD severity. Pts w/ periodontitis had 3X ods of RA (OR = 2.9) /https://t.co/bvOnFzbRcd https://t.co/cSxfiIR4iS
Dr. John Cush RheumNow
3 months ago
Follow the Money (4.23.2026)
Dr. Jack Cush follows the money and all the news that fits the Rheumatology Gab for this past week.
https://t.co/nEWINTOw6L https://t.co/a4oZxqwYhv
Dr. John Cush RheumNow
3 months ago
True or False: The DESIR axSpA cohort study found a significant association between NSAID use and incident hypertension over 10 years.
See if you got it right in the latest RheumIQ quiz at https://t.co/N5rfozh757. https://t.co/tkj0na3bkh
Eric Topol EricTopol
3 months ago
The impact oif obesity on the immune system.
Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports
https://t.co/j2tASpZlE0 https://t.co/5CgUrsFZru
Dr. John Cush RheumNow
3 months ago
APR: Difficult to Treat RA
Companion slide deck for the Advanced Practice Rheum: Difficult to Treat Rheumatoid Arthritis video, featuring Dr. Jack Cush.
https://t.co/GXnTicNTL6 https://t.co/ojOsMZ4sA7
Dr. John Cush RheumNow
3 months ago
Are uveitis and psoriasis independently associated with greater spinal radiographic progression in ankylosing spondylitis? Test your knowledge in the latest RheumIQ quiz at https://t.co/N5rfozh757 https://t.co/PjY1iuLv0X
EULAR has published a 2025 update for physical activity recommendations for patients with osteoarthritis (OA) and rheumatoid arthritis (RA).
Dr. John Cush RheumNow
3 months ago
Danish registry study of truncal (2,260) vs superselective (3,810) vagotomy (1977-95) vs general popul. (10:1). Truncal incr. RA risk (aHR 2.62), but selective did not (aHR 1.05. Neither had effect on OA risk https://t.co/dqejtN9TwY https://t.co/R0OJZTxd5T
Dr. John Cush RheumNow
3 months ago
Sun Pharma buys out Organon w/ $11.75 billion buyout. Both generated $6.2 billion in 2025 sales. Organon spun off from Merck in 2021, specializes in women’s health and is top 7 in biosimilars. Sun is into dermatology, ophthalmology and oncology-dermatology. https://t.co/zb4hucTqCJ
