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The Annals of Internal Medicine has published a predictive score to distinguish low-risk from high-risk inflammatory arthritis (IA) and who may benefit from risk stratification and preventive measures.
Retrospective study of 1877
pts. W/ granulomatosis with polyangiitis (GPA) on RTX found only 23% received TMP-SMX for a

Dr. John Cush RheumNow

3 years 2 months ago
Retrospective study of 1877 pts. W/ granulomatosis with polyangiitis (GPA) on RTX found only 23% received TMP-SMX for a median of 141 days. Prophylaxis was assoc w/ prednisone use (OR 3.96), MTX use (OR 1.48), ICU care (OR 1.95), hospitalization(OR 1.56) https://t.co/JRUC8HUwJU
IL-23 Inhibitor Performance in Psoriatic Disease

A single center real-world observational study shows three commercial

Dr. John Cush RheumNow

3 years 2 months ago
IL-23 Inhibitor Performance in Psoriatic Disease A single center real-world observational study shows three commercially available IL-23 inhibitors have high and similar drug survival and effectiveness in difficult-to-treat psoriasis and PsA. https://t.co/J3HIDBguj1 https://t.co/uqYf0Bdh0n
2023 ACR/EULAR Criteria for Calcium Pyrophosphate Deposition Disease

The prevalence of radiographic chondrocalcinosis

Dr. John Cush RheumNow

3 years 2 months ago
2023 ACR/EULAR Criteria for Calcium Pyrophosphate Deposition Disease The prevalence of radiographic chondrocalcinosis is estimated to be 4% to ≥10% in older adults, but the prevalence of symptomatic CPPD disease is unknown. https://t.co/yNQkEwRT3W https://t.co/YG7uBpDrPP
SGLT2 inhibitor (empagliflozin) given in a lupus mouse (MRL/lpr) model showed a renoprotective effect suggesting the val

Dr. John Cush RheumNow

3 years 2 months ago
SGLT2 inhibitor (empagliflozin) given in a lupus mouse (MRL/lpr) model showed a renoprotective effect suggesting the value of non-immunosuppressive therapies to improve renal function. Showed less -dsDNA Abs, proteinuria, renal nephritis damage https://t.co/iPhecsJeJX https://t.co/0TIy2hsPC1
Link Between Vitamin D and Psoriasis Severity

More than 8M people in the US experience psoriasis-a person’s vitamin

Dr. John Cush RheumNow

3 years 2 months ago
Link Between Vitamin D and Psoriasis Severity More than 8M people in the US experience psoriasis-a person’s vitamin D levels could play an important role in psoriasis severity, according to one of the largest studies to date. https://t.co/bHnYn87wQS https://t.co/JsloVaxHd4
Rheumatoid vasculitis (RV) metanalysis: RV decreased sincefrom 9.1 (1988-2000) to 3.9 (2001-2010) per million. RV risk i

Dr. John Cush RheumNow

3 years 2 months ago
Rheumatoid vasculitis (RV) metanalysis: RV decreased sincefrom 9.1 (1988-2000) to 3.9 (2001-2010) per million. RV risk increased w/ smoking, disease duration, seropositivity, males, HLA-DRB104, HLA-C3. Common: skin (65–88%), CNS(35–63%), cardiac (33%) https://t.co/O3G4CS1pdx https://t.co/I2RVKR20lX
Voclosporin in SLE - Long-Term Safety and Efficacy

The AURORA 2 study evaluated the long-term safety and efficacy of V

Dr. John Cush RheumNow

3 years 2 months ago
Voclosporin in SLE - Long-Term Safety and Efficacy The AURORA 2 study evaluated the long-term safety and efficacy of VOC upus nephritis (LN) patients and, after 3 years, demonstrated long term safety and efficacy following the one-year AURORA 1 study. https://t.co/YmKLuhyCVG https://t.co/X2u9iCckt7
EULAR/ACR Guidance on HLH/MAS

A EULAR/ACR task force has established evidence based, up-to-date guidance, and expert o

Dr. John Cush RheumNow

3 years 2 months ago
EULAR/ACR Guidance on HLH/MAS A EULAR/ACR task force has established evidence based, up-to-date guidance, and expert opinion on the evaluation, management and monitoring of patients with HLH and MAS. https://t.co/ZQQ75pyvAX https://t.co/t6lj5XaAwB
SGLT2 Inhibitors Reduce Gout Flares and CV Events

A cohort analysis shows that gout patients initiating sodium–gluco

Dr. John Cush RheumNow

3 years 2 months ago
SGLT2 Inhibitors Reduce Gout Flares and CV Events A cohort analysis shows that gout patients initiating sodium–glucose cotransporter-2 inhibitors (SGLT2is) had lower serum urate levels and fewer gouty flares requiring ED visits or hospitalizations. https://t.co/XCh7ulamwU https://t.co/dbOAtaflmb
MMWR: Arthritis Among Children and Adolescents

The CDC estimates that nearly 220,000 children and adolescents had arth

Dr. John Cush RheumNow

3 years 2 months ago
MMWR: Arthritis Among Children and Adolescents The CDC estimates that nearly 220,000 children and adolescents had arthritis during 2017–2021. https://t.co/S1dG60jJ1J https://t.co/rKQ64sopl2
RNase Treatment of Autoimmune Disorders

U1RNP complex, Ro/SSA and La/SSB are major RNA-containing autoantigens associa

Dr. John Cush RheumNow

3 years 2 months ago
RNase Treatment of Autoimmune Disorders U1RNP complex, Ro/SSA and La/SSB are major RNA-containing autoantigens associated with autoimmune disorders. https://t.co/RuXV3uAVz7 https://t.co/rWaKlmPnEe
Tofactitinib in PsA & RA: Nine Year Safety Data

A real-world, post-marketing surveillance (PMS) of tofacitinib in P

Dr. John Cush RheumNow

3 years 2 months ago
Tofactitinib in PsA & RA: Nine Year Safety Data A real-world, post-marketing surveillance (PMS) of tofacitinib in PsA and RA shows a consistent pattern of safety with no new safety concerns identified. https://t.co/erBi7JJtCY https://t.co/9tU361FkfU
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