Dr. John Cush RheumNow
3 years 5 months ago
Dr. Spiera's approach to PMR treatment
- prefers methylprednisolone
- rapid taper over 16 weeks
- consider GC sparing therapy (MTX, IL-6i)
@Rheumnow #RNL2023 https://t.co/EtlDZm1RSb https://t.co/cZSYwYRKNM
Dr. John Cush RheumNow
3 years 5 months ago
IL-6 for PMR
SPARE and SEMAPORE (Toci), SAPHYR (Sari)
2/2023: FDA approves sarilumab for PMR for inadequate response to corticosteroids or unable to taper off
Robert Spiera @RheumNow #RNL2023 https://t.co/gpBYXhguaV https://t.co/7tU1VBUb6F
Dr. John Cush RheumNow
3 years 5 months ago
Cochrane metanalysis of antidepressant use in managing chronic pain shows they dont work, with the small exception, duloxetine - at standard dose (60 mg) it was effective, but no benefit to using a higher doses https://t.co/SReueTu4VV https://t.co/ki0snBMS3z
Dr. John Cush RheumNow
3 years 5 months ago
"Ideally, you should get your TA biopsies within 2 weeks, but that's not always possible. Don't delay tx." @anisha_dua reminds us that bx can still be positive up to 8 weeks after steroid initiation. Just be aware of lesional changes with time. #RNL2023 https://t.co/uYBNrGzdQm https://t.co/Rvs0ewHzwb
Dr. John Cush RheumNow
3 years 5 months ago
Allergic Drug - Induced Arthritis
Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow. This week we delve into some odd associations, repeat drug warnings and the consequences of antirheumatic therapies.
https://t.co/AmpWG2Siii https://t.co/PwEgVHfDu8
Dr. John Cush RheumNow
3 years 5 months ago
MSK Symptoms from Dupilimab, an IL-4/13 Inhibitor
A new MSK syndrome of inflammatory enthesitis/arthritis/tenosynovitis has been described in atopic dermatitis (AD) patients treated with the IL-4 receptor antagonist, dupilumab.
https://t.co/xGPSA2oRis https://t.co/y7M42DlM7d
The second day of RheumNow Live 2023 held in March ended with a focus on axial spondyloarthritis, especially on the evaluation of the definition of the disease, the inheritance of it, and of course the treatment of it.
Dr. John Cush RheumNow
3 years 5 months ago
Brepocitinib in Active PsA
Brepocitinib is a novel tyrosine kinase 2/JAK1 inhibitor and has been studied in patients with moderately-to-severely active psoriatic arthritis (PsA), showing impressive efficacy at both 16 weeks and 52 weeks.
https://t.co/qzOVsLMkYe https://t.co/ouLyB131r8
Dr. John Cush RheumNow
3 years 5 months ago
QD Clinic - Audience Vasculitis Questions from RNL23
Audience questions from the live RNL 2023 meeting and the session on EVOLUTION AND ADVANCES IN VASCULITIS held on March 18, 2023.
https://t.co/mvimbucTnd https://t.co/uJzkZcbNLa
Dr. John Cush RheumNow
3 years 5 months ago
ICYMI: TNR - Vasculitis: Evolution and Advances
This is a replay from the live RNL 2023 meeting and the session on EVOLUTION AND ADVANCES IN VASCULITIS held on March 18, 2023.
https://t.co/OAI8NbSNes https://t.co/eDqqV9yZ9d
Dr. John Cush RheumNow
3 years 5 months ago
TNF Inhibitors and Acne? A literature review found 47 refractory acne pts Rx w/ TNFi; noting partial improvement (94%) or clearance (40%) & only 6% w/ adverse events. 17 pts had new-onset acne after Rx w/ TNFi for a different inflamm Dx. Odd! https://t.co/duHEIHBMyK https://t.co/br8NQZQE2r
Dr. John Cush RheumNow
3 years 5 months ago
The Schwartzman's (Monica and Sergio) discuss being in rheumatology as a family unit. We are so lucky in rheumatology to have many family connections! #RNL2023 @RheumNow https://t.co/hFbeGll2ut https://t.co/dfHnnbpNS8
Dr. John Cush RheumNow
3 years 5 months ago
Dr. Anisha Dua on Imaging in PMR:
- US of shoulders to eval for bursitis can increase specificity
- MRI better for pelvic girdle, but expensive
- Consider PET if lack of response to steroids, r/o malignancy
#RNL2023 @RheumNow https://t.co/tjhGlJPDWZ https://t.co/9h1FwfM0CP
Dr. John Cush RheumNow
3 years 5 months ago
Dr. Langford's take home for GPA. Remember to consider disease severity (will determine tx,) maintenance tx, and non-medical management including vaccination options for pts. #RNL2023 @RheumNow https://t.co/R6nrz7YXZr https://t.co/UVY0jDUGJ2

