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RT @DrScottLear: $520 billion is the estimated cost of physical inactivity from 2020 to 2030 @LancetGH: https://t.co/Jyn

Scott Lear, PhD DrScottLear

3 years 8 months ago
$520 billion is the estimated cost of physical inactivity from 2020 to 2030 @LancetGH: https://t.co/JynmtU9oCF Of the expected 500 million preventable cases of disease, 43% due to #depression and #anxiety. #MentalHealthMatters @fiona_bull https://t.co/sVjkceNGiq
No Special Heart Risk With JAK Inhibitors, Study Finds

Patients taking JAK inhibitors for RA experienced similar cardio

Dr. John Cush RheumNow

3 years 8 months ago
No Special Heart Risk With JAK Inhibitors, Study Finds Patients taking JAK inhibitors for RA experienced similar cardiovascular outcomes as those using the TNF blocker adalimumab (Humira), analysis of French national registry data indicated. https://t.co/i0oUoTSmqF https://t.co/qrJMQbpqus
Poncet’s disease: a reactive arthritis secondary to pulmonary M. tuberculosis

https://t.co/qMorRZBbi8

Dr. John Cush RheumNow

3 years 8 months ago
Poncet’s disease: a reactive arthritis secondary to pulmonary M. tuberculosis https://t.co/qMorRZBbi8
Anakinra in Pericarditis: A Systematic Review (comprehensive, full read) -Options include steroids, colchicine, NSAIDs,

Dr. John Cush RheumNow

3 years 8 months ago

Anakinra in Pericarditis: A Systematic Review (comprehensive, full read) -Options include steroids, colchicine, NSAIDs, pleuropericardial window, IL-1 inhibitors. ANAKINRA - 11 studies, 259 pts, all showing significant rapid resolution. https://t.co/i0LRp4E1tH https://t.co/lGLjJRB1G9

Three (3) Worst Drugs to use in #Lupus patients who want to be pregnant (MTX, MMF, CTX) #UTSWSLE2022 https://t.co/nBBUlW

Dr. John Cush RheumNow

3 years 8 months ago
Three (3) Worst Drugs to use in #Lupus patients who want to be pregnant (MTX, MMF, CTX) #UTSWSLE2022 https://t.co/nBBUlWXmhw
A beloved childhood game I enjoyed was Freeze Tag. Players would run to avoid being tagged by the person who was “It”.  If you were tagged, you had to “freeze” in your spot until someone was brave enough to come un-tag you.  The game ends when everyone is frozen or if people quit. For over 2 years, I have been living in a real-life “Freeze Tag” game and able to dodge COVID19, until now. Sitting in my room symptomatic and frozen in
Data came from the UK Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort of early RA patients starting methotrexate (MTX) shows that in the first year, adverse events (AE) were common, but not serious.
Cool NEJM Case of Spinal Gout in 82-yr-old woman with 3-wk hx of severe LBP, rigors, anorexia, incomplete urination. Hx

Dr. John Cush RheumNow

3 years 8 months ago
Cool NEJM Case of Spinal Gout in 82-yr-old woman with 3-wk hx of severe LBP, rigors, anorexia, incomplete urination. Hx of PsA, CKD, CHF treated w/ Humira, HCQ, diuretics. Imaging tophi in spine, responded to steroids and allopurinol. https://t.co/Ny50BLk7H3 https://t.co/OOqjpmc1DA
TNF inhibitors Dont Increase Cancer Risk! 4592 RA pts:TNFi Rx (2296) vs matched DMARD Rx (2296) pts. TNFi had a lower c

Dr. John Cush RheumNow

3 years 8 months ago
TNF inhibitors Dont Increase Cancer Risk! 4592 RA pts:TNFi Rx (2296) vs matched DMARD Rx (2296) pts. TNFi had a lower cancer risk than DMARD Rx (IR 6.5 vs. 15.6 /1000PYs]). TNFi had Lower HR GI CA (0.432), breast CA (0.146), GU CA (0.220) https://t.co/RouhT57Qkx
Study of 1141 consecutive gouty pts finds 10 (0.9%) with "Shrinking Toes" in those w/ tophaceous gout (usually MTP1,2) -

Dr. John Cush RheumNow

3 years 8 months ago
Study of 1141 consecutive gouty pts finds 10 (0.9%) with "Shrinking Toes" in those w/ tophaceous gout (usually MTP1,2) - toe shortening mainly due to lytic bone collapse during articular tophus dissolution (esp in severe gout w/ severe erosions) https://t.co/K0DzvAYoAg https://t.co/JhZWtSK7K4
When balancing all these disease domains, individual phenotypes, and comorbidities, sometimes treatment decisions can feel like tossing a coin. Fortunately, numerous guidelines have been published to help us do better than tossing a coin…or do they? 
In the wake of the 2016 AAOS Guidelines, rheumatologists dutifully reduced the dose HCQ take by patients with SLE to some number south of 5mg/kg per day. Though I believe the ophthalmologists correctly interpreted a 2014 paper in JAMA Ophthalmology that quoted a much-higher rate of HCQ associated retinopathy than had previously been appreciated, they and subsequent guidelines published in the field of rheumatology lacked a critical piece of
COPA, a rare syndrome w polyarthritis, ILD, pulmonary hemorrhage, w excessive STING signaling. #RWCS2022
@RWCSmtg http

Dr. John Cush RheumNow

3 years 8 months ago
COPA, a rare syndrome w polyarthritis, ILD, pulmonary hemorrhage, w excessive STING signaling. #RWCS2022 @RWCSmtg https://t.co/EUv8sMK8dx
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