Wheeler et al. MUC5B assoc risk RA-ILD, OR 2.25. No significant additive interaction with race, smoking, disease activity @RheumNow #ACR22 Abstr#2250 https://t.co/Hw2oBawKsd https://t.co/DqCQIPpEyg

• Genetic and Environmental Risk Factors in Rheumatoid Arthritis-Associated Inter…

Abstr #2195 COVID PrEP in Rheum pts who did not seroconvert after 3rd dose - anti-SARS-CoV2 IgG levels ↑ after day 1 - Saliva IgG also ↑ up to day 14 - one reported COVID+ w mild symptoms @RheumNow #ACR22 https://t.co/um2JFNMhpj

Zuo @RayZuoMD @jasonsknight et al. High levels of anti-NET antibodies in 45% of aPL-positive patients May activate the complement cascade and contribute to brain white matter changes. @RheumNow #ACR22 Abstr#2269 https://t.co/JrjNvQRDim https://t.co/c4yXHLOmBJ

• Anti-NET Antibodies in Antiphospholipid Antibody-positive Patients: Results fro…

ILD in #scleroderma. #Scleroderma lung study III - NO DIFF between MMF + Pirfenidone vs MMF alone. Planned for 150 Pts but only 51 enrolled but p=0.9. A trial recruited during #COVID so difficult to enroll Abst#530 @RheumNow #ACR22 https://t.co/CBYEJ2YCVM

How does #COVID19 impact pregnant women with rheumatic disease? Does vaccination status make a difference? @RheumNow #ACR22 https://t.co/2oJ1RAeciN https://t.co/c9s6QRSOR4

• Impact of COVID 19 on Pregnancies in Women with RMD - YouTube

Baker et al. Optum database study. Tofa assoc reduced incident RA-ILD. aHR 0.33 (vs ADA) @RheumNow #ACR22 Abstr#2251 #ACRbest https://t.co/R5rQ3KcHnq https://t.co/8Nq0t4zqQK

• Reduction in Rheumatoid Arthritis-Associated Interstitial Lung Disease Risk in …

#Vasculitis #ACR22 highlights. #Rituximab more remission in clinical care for GPA - observational, less infections if 600 mg IV fixed q6 mo how long to continue? Abst#1084 and less flares w Rituximab maintenance in the MAINRITSAN studies abst#527 Ritux is new SoC in GPA @RheumNow

Aggarwal @docrota et al. ProDERM results on skin and QoL. Statistically significant improvements in CDASI (both activity and damage) and SF-36. @RheumNow #ACR22 Abstr#2239 https://t.co/vsnvYUla13

• Effect of Treatment with IVIG (octagam10%) on Skin Symptoms and Quality of Life…

Let's review how GCs induce #Osteoporosis 👇(every Rheum should know this!) 💊GCs have bone cell specific effects on: 💠Osteoclasts ⬆️resorption, survival 💠Osteoblasts ⬇️🦴formation & prolif; ⬆️apoptosis 💠Osteocytes ⬆️apoptosis & skeletal fragility #ACR22 @RheumNow @rheumarhyme https://t.co/n61OXkmRgr

Espinosa-Ortega et al. Effect of DM ab on damage (as per MDI) over time. Most damage in PM/Scl>seronegative>other abs @RheumNow #ACR22 Abstr#2241 https://t.co/g8xTRyw6NZ https://t.co/sR1tT2QmU3

• Autoantibodies and Damage in Patients with Idiopathic Inflammatory Myopathies: …

BKZ resulted in clinically meaningful improvements in FACIT-Fatigue and pain (PtAAP) in approximately half of pts w/ active PsA who are bDMARD-naïve or TNFi-IR. Abs 2119 #ACR22 @RheumNow https://t.co/29gzmMZRlG https://t.co/qziqGNxQih

• Bimekizumab Treatment Results in Improvements in Fatigue and Pain in Biologic D…

After 1st TNFi, cycling/swapping strategies both acceptable in PsA w/ similar retention rates. Further studies needed to perform survival subgroup analysis regarding different extra-articular manifestations and PsA subtypes. Abs 2149 #ACR22 @RheumNow https://t.co/SRPhSiGeUI https://t.co/EYDULe52A3

• Cycling versus Swapping Strategies in Psoriatic Arthritis: Results from the Rhe…

Luedders et al. Higher plasma MMP-7 and MMP-9 assoc development incident RA-ILD in RA patients @RheumNow #ACR22 Abstr#2252 https://t.co/woVErubytC https://t.co/r916r1AxtN

• Higher Matrix Metalloproteinase Levels Are Predictive of Incident Interstitial …

More PsA pts on DEUC vs PBO achieved each of the MDA components at 16 weeks. Abs 2136 #ACR22 @RheumNow https://t.co/OrrDWfvGty https://t.co/CdCQzmgOOO

• Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in a Phase 2 T…

🌟 COVAX register 🌟 🦠flares of IMRD following covid vax uncommon 👉factors associated with flare: ⬆️disease activity 🙋‍♀️ female 💊no DMARD @ vax 💊stop/⬇️ DMARD @ vax 👉⬇️ flare assoc with: 💥young 💉RTX @RheumNow #ACR22 Abst #2274 https://t.co/S892lKcEvS