Preterm delivery and HTN disorders in #vasculitis Abstract #0953 #ACR22 @RheumNow @StanfordRheum 🤰87 deliveries from 1991-2012 🤰Higher risk for preterm delivery (PTD) (RR 4), PPROM (RR 4), HTN dx of preg. (RR 3) 🤰Of spon. PTD, 17% born between 20-31 weeks

Can Neural Networks Answer Important Diagnostic Dilemmas in Rheumatology? #ACR22 https://t.co/TThsEQ7RDH https://t.co/ZHNlH3J0de

• https://bit.ly/3Adf2KM

Ab1676 #ACR22 SAPHYR: Sarilumab in Refractory PMR 52wk SAR 200 mg q2w + 14w taper GC v PBO+GC taper Primary endpt: sustain response at 52w Early term 2/2 COVID, 117 pt SAR remission 28% vs PBO 10%, p=0.02 Data consistent when removes CRP data PBO: more GCs 2/2 PMR flare @Rheumnow https://t.co/kHq3juULX1

How much does diet and exercise help in knee osteoarthritis? Pragmatic RCT (WE-CAN), n=823 a diet & exercise intervention program led to: - 10kg weight loss - some significant pain improvements We need to fund diet & exercise programs for OA patients! ABST1675 #ACR22 @RheumNow https://t.co/Ctm8ZoRF3o

Update on ACR Guideline on Prevention and Treatment of GIOP. Sequential Rx when initial OP Rx and GC discontinued https://t.co/TWdI728pCp Mary Beth Humphrey #ACR22 @RheumNow https://t.co/i320si4RJp

• http://bit.ly/3hFVMzc

Sarilumab (IL-6R inhibitor) in phase 3 trial for relapsing PMR (SAPHYR trial). Key inclusion: Disease flare while taking >7.5mg prednisolone Sustained remission: resolution of symptoms, normalisation of CRP, adherence to prednisolone taper @RheumNow #ACR22 #Plenary

Spiera et al. Sarilumab in refractory PMR (SAPHYR) - Phase 3 RCT. Significant effect of IL-6i. @RheumNow #ACR22 Abstr#1676 https://t.co/2MS441B8gU https://t.co/jBd7YJKrTs

• Sarilumab in Patients with Relapsing Polymyalgia Rheumatica: A Phase 3, Multice…

#ACR highlights - #pegloticase in #gout - less reactions and more benefit w #MTX MIRROR RCT. Better than no MTX. Will change my practice - if I can access to a #peguricase, I will Rx w concomitant MTX Abst#0001 #ACR22 @RheumNow

Updated ACR Guidelines on Prevention and Rx of GIOP Rx recommendations when new fractures occur after 12 months of initial OP Rx https://t.co/TWdI728pCp Mary Beth Humphrey #ACR22 @RheumNow https://t.co/wHANvymd5R

• http://bit.ly/3hFVMzc

Updated ACR Guidelines on Prevention and Rx of GIOP OP Rx in special populations https://t.co/TWdI728XrX Mary Beth Humphrey #ACR22 @RheumNow https://t.co/0h72a4jXmG

• http://bit.ly/3hFVMzc

PATCH study, 👁 safety data in children 5 yrs after birth In utero HCQ exposure does NOT: -impact retinal morphology (OCT) -reduce significantly retinal thickness https://t.co/D7SgPG6PX4 Abs#1647 #ACR22 @RheumNow

• In Utero Exposure to Hydroxychloroquine Does Not Associate with Ocular Toxicity…

WE-CAN pragmatic RCT on community-dwelling ♂️&♀️ >/=50y w/ knee #osteoarthritis & obesity: 💠Diet + exercise = significant weight ⬇️and ☑️WOMAC pain score, WOMAC function, 6min walk distance & SF-36 HRQoL 🍽️+🚶‍♀️in OA? = Yes we can! #ACR22 @RheumNow @rheumarhyme https://t.co/Ty2boH52HC

Ab1675 #ACR22 WE-CAN - Knee OA 823 randomized pts, 18 mo: Intensive Diet & Exercise (D+E) Primary endpt: WOMAC pain - 32% reduct in pain in D+E, vs 24% (PBO) 20% more likely: clinically meaningful improve Improved BMI, 6MW, HRQoL, activity Pain Rx, depression: no change @RheumNow https://t.co/Su2g4Z38FV

Does diet & exercise work for knee pain in #osteoarthritis? Pragmatic trial in 3 community sites. 823 RCT, 80% completed -control was education &meetings vs diet&exercise;more intense. 101kg, 77% F, age 65. Diff modest-favoured diet & exercise-works a bit #ACR22 @RheumNow #1675 https://t.co/akjEjVprJl

Pain in #psoriaticarthritis might not be all inflammatory.. In this study presented by Dr F Sunzini: 👉PsA pts w/⬆️FM scores had⬆️functional brain connectivity bet mid-post IC & thalamus, phgyrus & PFC ..so consider nociplastic pain too & adjust mgt #ACR22 @RheumNow ABST#2256 https://t.co/suCAvx0pD5