Acetaminophen had more diarrhea and transaminitis than placebo in RCTS. In nonrandomized studies there were 1.4 times more UGI bleeds but likely channeling bias. Ok for CV events in RCTs; mixed results in uncontrolled studies for CV and renal. @RheumNow #EULAR2019 0P0019-HPR https://t.co/Y8f87jnxbR