Metformin, was given to a mouse model Sjogrens (NOD)/ShiLtJ mice) & reduced salivary inflammation, IL-6,TNFα, IL-17 mRNA, improved salivary flow rate, suppressed effector T cells, inducec regulatory T cells & B cell diff. Why are mice so easy, SS so tough? https://t.co/yC5fJIBBEx