UK pts w/ hemochromatosis homozygous for HFE p.C282Y finds men 40-70 w/ incr risk of Hemochr Dx, (OR 411), liver Dz (4.3), RA (2.23), OA (2.01) & DM (1.53). Heterozygotes w/ hemochromatosis was more common but morbidity was modest. https://t.co/8NyRRJGqTl