Amongst 192 patients w/ ANCA Assoc. vasculitis there were 95 severe infections (25%; 26/100PYs). TMP/SMX prophylaxis lowered risk of severe infections by 70% (HR 0.30). Risk was higher w/ age, bronchiectasis, endobronchial dz, COPD. https://t.co/aDEGNuwsEH