Provocative study in pre-RA. SC Abatacept in patients with pre-clinical RA can: -improvement MRI inflammation -⬇️evolution to clinical RA at 6 months -No new safety signal Yes, but we need longer term follow-up and an estimation of NNT. #OP0505 @Rheumnow #ACR2021 https://t.co/2P1Yk3IyeR