RT @KDAO2011: Risks for RA: - chromosome 6 has HLA risk genes encoding HLA-I and -II - HLA-DRB1 *04:01 and *04:04 stonrg
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Risks for RA:
- chromosome 6 has HLA risk genes encoding HLA-I and -II
- HLA-DRB1 *04:01 and *04:04 stonrgly assc w/ RA in white Americans/Europeans
- the Shared epitope increase risk for RA & severe disease; high assc with ACPA+
Protective➡️HLA-DRB1*13:01 @rheumnow #ACR21 2/2
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