⭐️C-OPTIMISE: Early, active AxSpA on certilozumab (CZP) 200mg q2w x 48w. Then, if remission, randomized to CZP q2w vs q4w vs PBO x 48w ➡️No flare in PBO BUT w/ ↑: *️⃣ASDAS + BASDAI *️⃣CRP + fecal calprotectin Thus, keep some dose of CZP on! Abst#0916 #ACR21 @RheumNow https://t.co/DT8FKHAhr0