Avoid IFX drug holidays! In this study 400+ pts Dvlpmt of ADAs associated w/ ▶️RA vs. SPA OR 2.1 ▶️Smoking OR 1.8 ▶️Drug holidays > 11 weeks OR 4.1 ▶️High DA OR 1.5 while ◀️Concomitant IS drug OR 0.4 ◀️ IFX dose increments OR 0.4, were protective #ACR21 @RheumNow #Abst1525 https://t.co/cxx7aWX5wh