Gout guidelines Allopurinol over febuxostat, dose low &slowly increase, T2T for serum Uric acid. Only Febuxostat if allopurinol failure/hypersensitivity. Only if failing with flares &tophi use peguricase. flares: colchicine steroids or NSAIDs #ACR @RheumNow https://t.co/ec6bOs5Hxo