Severe subtype of #sJIA HLADRB1*15:01 known to be associated with adverse drug reactions to biologics. prospective cohort - 65pts. - Anakinra effective irrespective of HLADRB1*15:01 - No difference in eosinophilia - Recommend not to wait to start tx @rheumnow #ACR22 abst#L12 https://t.co/LX5lMJOKRf