Some RA patients do well. Some do badly, and get frail even before the age of 65 (6% of pts). These are the ones that get hit by infections with b/tsDMARDs: see below from MarketScan data. These are the patients we need to watch & protect! ABST2217 @NamrataRheum #ACR22 @RheumNow https://t.co/DXZjFDnCcn