
Study of 21 Downs syndrome pts shows DS to be an autoimmunity-prone state, with a steady-state cytokinopathy, and evidence of hyperactivated CD4 T cells and ongoing activated B cells (CD11c+) - all contribute to a breach in immune tolerance. https://t.co/UUEByfBrqk https://t.co/ekq8AHYlxQ
09-03-2023