REMS is nothing to sleep about Not REM sleep but FDA may impose risk mitigation strategies post marketing. It applies to some drugs such as Coxibs and Actemra vs Etanercept ENTRACT RCT for CV safety and Belimumab in SLE for safety. All equally safe #RWCS2020 @RheumNow https://t.co/b3rDlcABwL