Cytokines/biomarkers from IL-23/IL-17 pathways are Increased in psoriasis. Subanalysis of phase 2 254 pt PsO trial revealed that 12 wks of deucravacitinib assoc w/ reduction in IL-17A, IL-17C, beta-defensin, PI3 - decreases correlated w/ PASI changes https://t.co/Ii381B2mZx https://t.co/vXDyLUsKPi
Links:
Pharmacodynamic Response to Deucravacitinib, an Oral, Selective, Allosteric TYK…
https://buff.ly/4h3jFuy
Oct-14-2024


