GLP-1 Agonists Alleviate Knee Osteoarthritis In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis. https://t.co/3ETmyFWpWY https://t.co/wn1QDwKi3R