We often see patients with MTX lab abnormalities but How frequent is MTX toxicity? Retrospective study 2500pts Rochester Epidemiology Project cohort 60% w/ ever lab abnormalities, but 4% attributed to MTX 0.87/100 patient year Organ injury event 0.02/100 patient year = 5 in https://t.co/w8oYUjj5Yp