NLRP3 inflammasome activation triggers PAD (2, 4) release from human neutrophils, increasing citrullination of intracellular proteins (CCPs) and driving the pathogenesis of #RA. Further proof: , PAD concentrations and PAD activity correlate with IL-1β.https://t.co/pRQy0ECG5d https://t.co/HExIhebJ4u
Links:
NLRP3 inflammasome promotes PAD2/PAD4 release and protein citrullination in rhe…
https://buff.ly/y6eDWy8
May-25-2026


