Cogan's syndr is a rare autoimmune dz, all ages (20-30s) & races (whites) w/ ocular (interstitial keratitis) & audio/vestibular Sx (deafness, vertigo). Less: HA, fever, myalgias, aortitis, heart. No Dx test; 1/3 have another systemic dz. Rx: steroids https://t.co/e3sstsxO5R https://t.co/CQ3UfBqO0e

Study of >1million people/17 countries shows prevalence of NAFLD (fatty liver) to be 32·4% - higher than prev estimates & growing fast rate. Prevalence increased from 25·5% (2005) to 37·8% (2016); NAFLD incidence is 46·9 cases per 1000 person-years https://t.co/npESZ2YWgd https://t.co/podfxma5vo

Network metanalysis & review looked at Biologics & remission in Crohns disease (25 RCTs; 8720 pts). -Compared to PBO Rankings were #1) infliximab 5 mg/kg (RR=0.67), #2) risankizumab 600 mg, #3) upadacitinib 45 mg. RIZ was 1st in biologic-naïve pts https://t.co/JFTEpqSJ6c https://t.co/65vbZkLmpC

CDC has updated COVID-19 guidelines - People COVID exposed: no need to quarantine, regardless of Vax status, but use mask x10 d & get tested day 5 - Surveillance testing without Sxs not recommended - if COVID test +, should isolate at home x 5d https://t.co/whVQShsSJR? https://t.co/KnYtJ7BfOO

Fatigue is Under-Appreciated in Psoriatic Arthritis Patient-reported fatigue is high in patients with psoriatic arthritis (PsA) and often goes under-recognized by physicians. https://t.co/mb80NHH0dr https://t.co/an4rq1BPut

NEJM - Lupus Pernio in Sarcoidosis - 71 yoM w/ red nodules on his nose, ears, fingers, and toes. The lungs were clear on auscultation. Angiotensin-converting enzyme level of 102. https://t.co/BUvO9Y0rzs https://t.co/AhK6VMVBlD

Retrospective study of 99 Henoch-Schönlein purpura (HSP) pts complicated by GI bleeding (61 mild; 38 severe). Severe GIB assoc w/ sufmmer Onset, facial rash, HI D-dimer (>0.89 mg/L) & neutrophil-to-lymphocyte ratio (NLR >10.56). https://t.co/9QXEFXbRiV https://t.co/T3gX92EWQ0

Population study of 28,756 individuals shows cognitive function is linked to sleep duration. Those with low (≤4 hrs) or excessive ( ≥10 hrs) sleep showed statistically significantly cognitive decline than reference group (7 hours per night) https://t.co/SDXmItMxO3 https://t.co/wMYB1u0hDb

Should you do sural nerve biopsy (SNB) to Dx vasculitis? Study of 91 pts undergoing SNB suggests the SNB must be off sufficient length to improve Dx yield. 40/91 (44%) showed vasculitis. +SNB assoc w/ longer SNB sample, other organ Sxs & +ANCA https://t.co/aSC9xUfRFB https://t.co/lLRnrqXKaw

US national study of shows pregnancy in inflammatory bowel disease pts has higher risks for: - gestational diabetes (AOR) - HTN complications (1.35) - Pre-term births (1.41) - Fetal growth restriction (1.27) - Fetal death (3.21) https://t.co/3XTrrrNmoe https://t.co/udl7dXT5IF

CDC Reviews Monkeypox - 99% men, 94% male-to-male sexual contact; less prodrome; rash (100% including genital), fever (63%), chills (59%), and lymphadenopathy (59%) https://t.co/OUQPXh0RQq https://t.co/GWpomlj5PX https://t.co/VC6mg35J1Q

150 PsA pts assessed preferences in chosing biologics (of most to less preferred): 1 Oral over SC or IV routes 2 Avoiding severe side effects 3 Resume normal activity 4 Avoid infections 5 Improve enthesitis & 6 psoriasis 7 remission 8 Joint pain https://t.co/kE3qtTWBhH https://t.co/KKcsQqEYKf