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#EULAR2022 AAV Update Reccs (1/n): 1.Tissue biopsy recommended to establish diagnosis and eval pts w/ possible relapse @rheumnow https://t.co/qsD2PPfOPU
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 1 month ago
#EULAR2022 POS0235: Filgotinib Safety in RA for Median 2.2 years: ▶️No new safety concerns from 2020 report with shorter f/u ▶️Adverse events stable, or decreased, from early studies @Rheumnow https://t.co/DO15Tqim4n
Eric Dein @ericdeinmd ( View Tweet )
4 years 1 month ago
#EULAR2022 Updated Reccs for EGPA (1/n) 👉 Use high dose GC +CYP or RTX for remission induction of #EGPA @rheumnow https://t.co/2Au5UrNKs3
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 1 month ago
Secukinumab 300mg at week 52 in ankylosing spondylitis patients (who did not achieve inactive disease with SEC 150mg at week 16) experienced similar clinical response and safety profile regardless of dose escalation. #EULAR2022 @RheumNow #ABSTOP0023 https://t.co/7LeZMMWeRC
Robert B Chao, MD @doctorRBC ( View Tweet )
4 years 1 month ago
SELECT-AXIS 2 trial demonstrated efficacy and safety of upadacitinib in treatment of non-radiographic axSpA. ASAS40 at week 14 (45% vs. 23% placebo). No MACE, VTEs, IBD, death. @RheumNow #EULAR2022 ABST#OP0016 https://t.co/vyky0JJJjS
Robert B Chao, MD @doctorRBC ( View Tweet )
4 years 1 month ago
More #EULAR2022 Updated Reccs for #AAV 👉use clinical assessments & not just ANCA or CD19+ B-cell testing to inform decision for change in Rx. 👉measure Ig levels w/RTX prior to each course of RTX (to eval for immunodeficiency) 👉use PJP prophylaxis in high risk pts @rheumnow https://t.co/kYPQnLvcCK
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 1 month ago
Combination tx of NSAIDs and TNFi (celecoxib and golimumab) did not show significant superiority compared to TNFi alone in slowing radiographic progression for treatment of radiographic axSpA. There was a numerical reduction however. #EULAR2022 @RheumNow #ABSTOP0018 https://t.co/gUZAwd92dK
Robert B Chao, MD @doctorRBC ( View Tweet )
4 years 1 month ago
@Rheumnow #EULAR2022 POS0240 ▶️ In 2021, 73.6% of Belgian RA patients staring a JAKi, started a 2nd generation JAKi (UPA, FIL). Predictors for 1st generation usage (BAR, TOFA): older age, prior DMARD therapies. What would you start as a first JAKi?

Eric Dein @ericdeinmd ( View Tweet )

4 years 1 month ago
Household Cleaning is dirty business at least if you have #rheumatoid #arthritis as silica exposure from laundry and cleaning products were associated with RA ILD. #EULAR opening day. #ClinicalPearl #EULAR2022 @RheumNow #OP0006 https://t.co/OJQMy9Fe9m
Janet Pope @Janetbirdope ( View Tweet )
4 years 1 month ago
Immune Checkpoint Inhibitor Associated Arthritis Immune checkpoint inhibitors (ICIs) have dramatically improved outcomes in numerous cancers but have been hampered by a growing spectrum of immune-related adverse events (irAEs). https://t.co/Eno0TcWlNX https://t.co/XjkBlUEFxk
Dr. John Cush @RheumNow ( View Tweet )
4 years 1 month ago
ACR21: conditionally recommends against steroids with starting csDMARD #EULAR2022 recommends with rapid GC dose reduction and discontinuation Which is better recommendation? @RheumNow

Eric Dein @ericdeinmd ( View Tweet )

4 years 1 month ago
#EULAR2022 RA updated reccs w/ minor changes: start MTX+GC, reduce GC rapidly, JAKi are recc only for pts w/o risk factors for CV or malignant dz (not sure I agree with this last one if the JAKi is the best drug for the pt and there are little options avail) @rheumnow https://t.co/CXyyCi6LVI
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 1 month ago
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