Tweets
At a time when most American doctors have never seen measles, I think we should stop calling things morbilliform.
Adam Cifu @adamcifu ( View Tweet )
4 years 2 months ago
Differential diagnosis of dysphagia - when due to autoimmune dz is called Autoimmune neurogenic dysphagia - causes include inflammatory myopathies,inclusion body myositis, myasthenia gravis, Guillain–Barre, MS, NMO, paraneoplastic neuropathies https://t.co/oA0cPVJ5pJ https://t.co/58MyQwmxhL
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
⭐️Ethics of placebo-controlled trials in PsA ➡️move toward active comparator designs. Need to use measures of deeper response (e.g., ACR 50, PASI100).
⭐️Assesing safety: LTE studies not adequate. Use of phase 4 studies or observational data but beware confounding by indication
Rheum Cat @rheum_cat ( View Tweet )
4 years 2 months ago
SARS-CoV-2-infected alveoli (specifically N protein-coding plasmid alone) induces IL-6 production. Also, COVID-19 Sera also induced IL-6, moreso in those w/ severe disease. anti-N Ab promotes IL-6 production & may lead to cytokine storm https://t.co/jfPNwZM0g8 https://t.co/FwIs11i2qc
Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
Tonight!: Join us for Tuesday Night Rheumatology on Spondyloarthritis Spectrum. This webinar will feature lecture highlights followed by live audience Q & A.
7pm ET | Join on Zoom or watch LIVE on RheumNow Twitter, LinkedIn and Facebook.
https://t.co/Y6MtCItIxw https://t.co/ysRM3cWyYa
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
Data from Scleroderma Lung Study (CTX vs MMF in PSS) shows that early progression of ILD by CXR scoring (≥ 2% at 12 or 24 months) experienced significantly worse long-term survival than those with stable Xrays (P = .014). https://t.co/BVy0WEE6G8 https://t.co/e6NN7nxNDt
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
24 week, Phase II RCT of baricitinib in 314 active #SLE patients showed significant reductions in levels of dsDNA, IgG, Sm & ACL Abs; but had no effect on C3/C4, RNP, SSA, SSB. Changes in dsDNA did not correlate with SRI-4 responses though.https://t.co/cF6rHbtvf9 https://t.co/zXnUImaLHF
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
FDA has approved baricitinib (Olumiant) for the Treatment of Certain Hospitalized Patients with COVID-19 who require supplemental O2, mechanical ventilation, ECMO. Rec dose: 4-mg once daily for 14 days or until hospital discharge https://t.co/RiEp01tc0v https://t.co/f3RvUAzdRp
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
Cool NEJM Case of Spinal Gout in 82-yr-old woman with 3-wk hx of severe LBP, rigors, anorexia, incomplete urination. Hx of PsA, CKD, CHF treated w/ Humira, HCQ, diuretics. Imaging tophi in spine, responded to steroids and allopurinol. https://t.co/JgH2bPsDeu https://t.co/RAPNxohe55
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
New podcast available on Methotrexate Monitoring. Download wherever you get your podcasts.
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.
https://t.co/TQiUMdS4R0 https://t.co/vgejiV3hUl
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
Study of 198 RMD pts, vaccinated 91% JAKi and 80% MTX mono pts were Ab+ for spike protein. Adjusting MTX or JAKi did not significantly alter the immunogenicity (S1 spike Abs). DMARD adjustments w/ COVID-19 VAX may not be needed. https://t.co/ebw172M5I4 https://t.co/vjXqTbuD5t
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
ASCORE: Seropositivity Favors Abatacept Drug Survival
The ASCORE study evaluated efficacy, safety, and drug retention (durability) of ABA in moderate-to-severe RA and found consistently better ABA durability in those who were seropositive.
https://t.co/dLFC3dW4Tv https://t.co/LNCUIQjnGf
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Dr. John Cush @RheumNow ( View Tweet )
4 years 2 months ago
