Tweets
2 studies from NKF meeting shows gout occurs in 13.5% of CKD on dialysis; and seen in 17-28% of Stg 3,4 CKD pts. CKD w/ Gout has more bone/mineral Dz (40 vs 26%), CHF (21 vs 14%), DJD (17 vs 9%); >1/3 NOT on urate lowering therapy https://t.co/sn40xqxRyg https://t.co/ewb0tpWukw
Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
Can IL-22 differentiate between IL-17 & TNF inhibitor #PSA responders? Pilot study 2 cohorts 81 PSA pts showed both biologics worked but somewhat better response in IL-17i Pts w/ low IL- & TNFi responses w/ high IL-22 levels. https://t.co/txyNl2OwTP
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
ICYMI: Copenhagen study of COVID & Rheum disease (AIRD)
▶️ COVID+ AIRD pts have 10x more hospitalizations (7% vs 0.7%)
▶️ Only RTX assoc w/ COVID hosp (adj OR 14.6)
▶️ IgG Abs increased if AIRD pt hospitalized
https://t.co/VtERRZsGb8 https://t.co/ZwdfNJaAS7
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
ICYMI: Males respond better than females? Ixekizumab trials in #PSA - 676 pts in Two Phase 3 RCTs - females had lower response rates than males in all measures (ACR20/50/70; MDA; DAPSA) F had ⬆️HAQ, enthesitis, but ⬇️CRP https://t.co/sjVJZ8uQA3 https://t.co/l7B2ICZWaJ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
ICYMI: SLE study from BC, Canada shows that among 3062 incident #SLE patients 96% received antimalarial (AM) Rx with only 40% adherent. Over a 6.4 yr F/U, 242 (8%) died. AM adherence was assoc w/ a 71% and 83% lower risk of death https://t.co/0uKAKJVxri https://t.co/KuvEA2pzrg
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
In #rheumatology ,the longer you see pts,the more they rely on you for issues related to their disease, including
➡️ Dental/mental Health
➡️ Nutrition/exercise/sleep
➡️ PT/OT/rehab
Looking for resources pertaining to rheumatology to self educate.
#RheumTwitter #MedTwitter
Tanmayee Bichile, MD @BichileT ( View Tweet )
4 years 3 months ago
Register for Tuesday Night Rheumatology today! Join us as we discuss the controversies in PsA when it comes to diagnosis, treatment strategies, therapeutics and more.
https://t.co/YXAmzvPfeK https://t.co/jtSd0Ig5IT
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
Administrative Claims data from British Columbia studied 100,358 OA pts and compared tramadol v NSAIDs. Tramadol was associated with higher All-cause mortality (HRs,1.2 to 1.5), more VTE (v diclofenac, HR 1.7), more hip Fx (HR 1.6) https://t.co/5Lei6Lgtpf
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
Kids With Psoriasis Maintained with Long Term IL-17A Inhibitor
https://t.co/CfAjvc9XWg https://t.co/RaD5qqPM3a
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Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
No Benefit to More Intensive Urate Lowering in Gout
While treat-to-target (T2T) is commonly advocated in gout management, it is unknown if T2T (or more intensive T2T) may result in less bony erosions in gout.
https://t.co/uag4fJ4FSi https://t.co/djniwFl491
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
Copenhagen study of COVID & Rheum disease (AIRD)
▶️ COVID+ AIRD pts have 10x more hospitalizations (7% vs 0.7%)
▶️ Only RTX assoc w/ COVID hosp (adj OR 14.6)
▶️ IgG Abs increased if AIRD pt hospitalized
https://t.co/WYXbt2FJJi https://t.co/K2NGJsKVVc
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
Large metanalysis looks at Quality of Life outcomes w/ Therapies in #PSA
37 RCTs = 14.115 PsA pts
◾️ bDMARDs > PBO
◾️ bDMARDs = MTX (or Tofa)
◾️ bDMARDs + MTX > MTX
https://t.co/6DDsVjcdcr https://t.co/ljb6AOH3UK
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 3 months ago
