ICYMI: Adalimumab Addition vs. Methotrexate Escalation in Psoriatic Arthritis https://t.co/q0uIjLrT3G https://t.co/ehgEUSrbPg

ICYMI: Swedish study found 1774 systemic sclerosis (SSc) pts in 2015 w/ median age 65 yrs (84% women) = prevalence=22.7 per 100,000 . Incidence (2004-2015) was 11.9 per 1,000,000 PYs - incidence remained stable; F were 5x more common than M. https://t.co/NPZUg4CEjA https://t.co/V3H381KpHU

Ask Cush Anything! Have a rheumatology question or case for Dr. Cush? Submit it here and we may feature it on an upcoming podcast. https://t.co/KgPIeScthr https://t.co/nk4re9mlcH

High disease trajectory despite disease control (^HAQ > DAS28) in RA is more likely with higher pain, fatigue & depression. 10 ys study of 2500 RA pts from NOAR, ESPOIR, ERAN) https://t.co/mrB7fog6PD https://t.co/tqm3LPkOdM

98 axial SpA women with 335 pregnancies (279 live births) shows preterm birth ( (12.5 v 5.2%), preeclampsia(6.8 v 2.8%) & LBW (8.2 v 2.9%) more prevalent in axSpA, possibly due to incr disease activity during pregnancy & postpartum https://t.co/Bp8QjBXg2K https://t.co/j0xKVvSPIH

TENS does not work! Multi-centre, trial in 220 active Knee OA pts pitted TENS vs placebo TENS for 3 Wks. Using WOMAC pain scores there was no difference between TENS and placebo TENS (mean diff -0.06; P=0.74). No diff in AE or 2ndary outcomes https://t.co/4Aw9s1zfBQ https://t.co/gwdK6nbKLB

Poor Outcomes in Lupus Patients Not at Target A prospective, longitudinal SLE cohort study examined outcomes and showed that failure to control SLE was common/associated with poorer outcomes including organ damage, glucocorticoid exposure, and more. https://t.co/wQMmPgbmWF https://t.co/ROeZU56cfy

Effect of Intraarticular Steroid Shots on Knee OA Outcomes In patients with osteoarthritis of the knee, intra-articular injections of steroids did not increase rates of either disease progression or subsequent knee replacement surgery, researchers said. https://t.co/KlNj1GABlb https://t.co/2npPTNSlSA

Having the MUC5B promoter variant increases odds of RA-ILD w/ earlier onset in RA, esp w/ older age of RA onset. Mass Gen Biobank study of 1,005 RA pts; MUC5B found in 15% w/ incr risk of RA-ILD (OR 3.34) & RA onset after 55 yrs (OR 1.52) https://t.co/5odVWnpuxo https://t.co/zeKxADTSBZ

Montreal General Hosp SLE cohort study of 489 SLE pts - 35% have Raynauds phenomena; RP in SLE assoc. w/ Female (OR 2.43), White (OR 1.85), CNS disease (OR 1.98), RNP Abs (OR 3.0); negatively assoc w/ hemolytic anemia & cellular casts https://t.co/dUxAAIIyya https://t.co/ttIt9pDsTh

Aging & Inflammatory Rheumatic Dis is a growing Problem: - Multimorbidity drives polypharmacy & compounds safety risks - More malnutrition, sarcopenia & frailty - Phenotype of Rheum Dz changes w/ age - Tx differs for the elderly - Elder RA is undertreated https://t.co/J2q0mEOqDd https://t.co/VfolGeYx6V

New download available. DMARD and Biologic Safety Prescribing https://t.co/zXE7HwgAYU https://t.co/pMQGPU6KCM