TNFi and pregnancy No association w/ congenital anomalies/infant infection Discontinuation of TNFi before wk 24, increases risk of disease flare Biologic lvls low in breast milk Does not affect vaccine response Live rotavirus vaccine did not cause infection @RheumNow #RNL2022 https://t.co/ZNdjf5qNDb

#ClinicalPearl You really are what you eat! Guy micobiome is ‘off’ in animal 🦒 & human studies in #inflammatory #arthritis compared to healthy population. But is it 🐓 or 🥚? Possibly both. @JoseScher @RheumNow #RNL2022 https://t.co/6nKsovlSgf

Ok 💩 results #ClinivalPearl one fecal transplant in active #PsA did WORSE than sham Rx. Those doing high colonics - no idea why one would- likely also a waste {pun intended} Dr Jose Scher presented RCT #RNL2022 @RheumNow https://t.co/FDlOvPdzvl

If you don’t treat active #rheumatoidarthritis while woman 👩 is pregnant, you may do more harm to 👶🏻. Look at the data @UmaMahadevanIBD #RNL2022 @RheumNow https://t.co/6P94IdfS15

ACR recommendations fro TNF biologics during pregnancy! Why stop at third trimester?! i agree do not rock the boat!! @UmaMahadevanIBD @RheumNow #Rnl2022 https://t.co/NEMEV3ThkF

Pregnancy exposure to biologics didn't increase risk of infection to THE FETUS !! @UmaMahadevanIBD @RheumNow #Rnl2022 https://t.co/rdEaake6ey

Other data on TNF and pregnancy! To maintain pregnancy and avoid complications , decrease inflammation! how? by continuing TNF! ▶️No increase risk of infection or vaccination response. @UmaMahadevanIBD @RheumNow #Rnl2022 https://t.co/mcEMDzNlyH

What about live vaccines?! is there any increase risk of complications ?! @UmaMahadevanIBD @RheumNow #Rnl2022 https://t.co/x74RoWNnLc

Pregnancy and Biologics @UmaMahadevanIBD sharing excellent information on how stopping drugs can lead to more harm: Lacking data that RA improves during pregnancy Provider bias? Steroids can increase complications in pregnancy @RheumNow #RNL2022 https://t.co/jtCnD4wTag

And finally, Day 1 will close out with POD 4: Spondyloarthritis Spectrum at 5pm ET. Join Dr. Philip Mease at his presentation on Axial Psoriatic Arthritis. #RNL2022 https://t.co/TInpHYteOx