Tweets
Should we use colchicine in COVID-19? Mainly mixed results; not likely effective in sick hospitalized patients but may have utility in early infections https://t.co/wecWjSIbEG
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
ICYMI: NEJM study of ~2000 persons showed that prior PCR proven SARS-CoV-2 infection was effective at preventing Symptomatic Reinfection against alpha variant (90.2%), beta ( 85.7%), delta (92%), but not omicron variant (56%). https://t.co/UkvDUH6alK
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
ICYMI: Retrospective study of 179 antiphospholipid syndr pts, looked at noncriteria findings- their presence incr relapse rates (59% vs 34%;p=0.018) triple positivity & need for Rx. (cytopenias, APS nephropathy, livedo, CNS, Libman Sachs endocarditis) https://t.co/i7UItlDcHd
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
ICYMI: Women Heroes in Rheum:
- Barbara Ansell - JIA
- Nanna Svartz-SSZ
- Gertrude Elion - Nobel Prize for allopurinol, AZA
- Tsai-Fan Yu - gout Rx
- Mary Betty Stevens - lupus/vasculitis
- Marian Ropes - 1st F ARA president
- Fionula Brennan-TNFi
& more
https://t.co/0kxrXo5fr3 https://t.co/QfCDxkfYRi
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
ICYMI: Approximately 61% of patients with rheumatoid arthritis or psoriatic arthritis who use methotrexate report side effects following weekly dosing, including fatigue and nausea, according to data published in Rheumatology and Therapy https://t.co/65OMw9A96h
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Data from 2 phase III studies of psoriatic arthritis using tofacitinib, adalimumab shows that a significant meaningful clinical response is achieved in 29-53 days -- why then are we not making go vs no-go decisions with modern biologics at 6-8 weeks? https://t.co/F56P9c3Rb5
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
CARRA Registry looked at TNFi use in JIA and found a nearly 3 fold increased risk of psoriasis. 8225 pts w/ 3.9 yrs of F/U. 54% recv TNFi; the aHR of new onset of psoriasis after TNFi exposure was 2.93 (2.15 to 3.98). MTX had lower risk (HR 0.45) https://t.co/Z6qvlS26M9
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Osteoarthritis Initiative study looked at Hand OA. Among 3588 participants, 41% had hand OA by xray and 12.4 % by Sxs. Over 4 yrs, 27.3 % showed Xray OA progression. More in women (DIPs)>men (MCPs), but less in blacks https://t.co/WRZYcL7zFH
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Scandinavian study of cardiac abnl. in idiopathic inflammatory myopathies showed prolonged QTc abnormalities was more common in IIM pts (16%) & Anti-Mi2, anti-Pl-7, elevated CRP are associated with prolonged QTc (potential biomarkers?) https://t.co/vkEDaum9aY
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Join Dr. Alexis Ogdie at RheumNow Live next month, as she leads a panel on RWE & Registries in Psoriatic Arthritis.
Attend on-site in Texas or virtually!
Invigorate, Instigate and Debate Rheumatology at #RNL2022
https://t.co/aTEWF9VsdN https://t.co/e2W5XpzztN
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Among 10,205 admissions for psychosis, 19% were tested for ANA, 15% of those were ≥1:160; BUT ONLY 4 patients met 2019 ACR/EULAR criteria for SLE, & 2 met criteria for Neuropsychiatric SLE - NPSLE prevalence of 1.5% ANA+ psychosis pts https://t.co/r2sTSVKC66
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
NEJM study of ~2000 persons showed that prior PCR proven SARS-CoV-2 infection was effective at preventing Symptomatic Reinfection against alpha variant (90.2%), beta ( 85.7%), delta (92%), but not omicron variant (56%). https://t.co/xlyGmJPRnj
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
