Tweets
FREED study (asympt hyperuricemic without gout) showed febuxostat x 24 mos dint alter carotid atherosclerosis, but at 3 years, (Substudy of 1004 pts), showed FEB signif lowered risk of CVA, CV, renal renal events and death (vs PBO) https://t.co/BS4wiIaYZv
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
New podcast available! Dr. Jack Cush reviews the news and journal articles from this past week on https://t.co/V10S4oVFsv. These reports are about better outcomes in Lupus; fewer Gout flares with T2T and the power of belief.
https://t.co/8sxDTiU9QD https://t.co/bc8A1FWkVS
Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ICYMI: Network metanalysis (28 RCTs, 12 504 pts) of Biologics & small molecules therapy in active ulcerative colitis. Upadacitinib 45 mg qd ranked 1st (RR 0.73) vs PBO, infliximab 5 mg/kg & 10 mg/kg ranked 2nd & 3rd. UPA > TNFi at remission. https://t.co/ne6yfBEJJz
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ICYMI: FDA has approved 2 JAK inhibitors for use in severe atopic dermatitis (eczema) - Abbvies upadacitinib (Rinvoq) and Pfizers abrocitinib (Cibinqo). https://t.co/6wdyN6NvVa https://t.co/RfliRSH5Kf
Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ICYMI: Annals of Internal Medicine describes a propensity matched comparison study of risedronate and alendronate, showing that, compared to alendronate, risedronate drug holidays were associated with a small increase in risk for hip fractures.
https://t.co/6qnMUzqV3E https://t.co/iIrahEuB09
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ICYMI: JAMA reports that between Dec 2020 and July 2021, COVID-19 vaccination saved nearly 241,000 lives, prevented 1, 133, 617 hospitalizations and prevented more than 14 million COVID-19 cases (all in 1st 6 mos of the COVID vaccines) https://t.co/q9TvLjtY9p
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ICYMI: Infliximab treatment of RMD/IMIDs by targeting drug levels (therapeutic drug monitoring) was superior to usual care in study with more sustained Dz control without worsening in 458 IMID pts Rx for 52 weeks (TDM 74% vs 70% standard Rx) https://t.co/KsnQxYXHkI
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
UCB announced positive top-line results from Phase 3 BE COMPLETE study, bimekizumab, in active psoriatic arthritis, who failed TNFi. Bimekizumab pts showed a 50% ACR50 at week 16, as well as signif improvements in PASI90, MDA, PGA https://t.co/pnhQKeUxKt
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
ACR 2021 Highlights: Comorbidities in axSpA Presentation
Sponsored by Novartis Medical Affairs
Tune into Dr Marina Magrey discuss axSpA comorbidities focusing on cardiovascular manifestations.
https://t.co/w1EnRapTaN https://t.co/v5ZDmpUq1b
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
3rd Vaccine Dose May Benefit ANCA-Associated Vasculitis Patients
https://t.co/UXUryaQ7Fz https://t.co/p40xND4lVP
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
The CDC's Advisory Committee on Immunization Practices recently recommended & approved 2 doses of the recombinant zoster vaccine for prevention of herpes zoster and complications in immunodeficient/immunosuppressed adults aged ≥19 years.
https://t.co/nk4feoUO5B https://t.co/6fR33fG5xw
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
791 knee OA pts studied for progression after steroid (GC) (n=629) vs hyaluronic (HA) injxn (n=162). Knee OA progression was similar between groups for JSN (RR 1.00) & K/L grade (1.03); but IA GC had slightly lower TKR (HR 0.75 [CI 0.51–1.09]) https://t.co/74eg2Zvdy1 https://t.co/soXb7bdq6O
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
