Tweets
NEJM: A 14-year-old boy was admitted to this hospital because of fatigue, fever, joint pain, abdominal cramping, and diarrhea. Start w/ Sore, throat, then polyarthritis (knees, Shoul), fever 39.4C. Very high WBC, CRP & lipase. Whats the Dx?
Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Biomarker study of 21 systemic juvenile idiopathic arthritis (sJIA) shows you can differentiate between active & inactive disease. From 69 biomarkers, these were predictive: IL-6, MMP1, S100A12 (p < 0.0001), HMGB1; but IL-18 elevated in both groups! https://t.co/m2yXTITzwY
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Single center comparison of pts with MAS vs malignancy assoc. HLH (mHLH) - overall MAS had less hepatomegaly (0 v 25%), double platelet #s (50 v 29Kµ/L), but lower sIL-2R (6814 vs. 27,972.0) and less mortality (22 v 44%, p=0.18). https://t.co/NGIaPTU0yT
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Register for RheumNow Live, March 19-20, 2022.
You can attend RheumNow Live in person in Irving, Texas - or, the comfort of your own home or office.
You can also receive CME credit!
https://t.co/fYyV75vAWm https://t.co/zOpCbBrzHJ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
New podcast available for download.
2021 Rheumatology Year in Review
https://t.co/0Lpo0IUBHp https://t.co/ysdwmQjeaS
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
There were significantly fewer FDA advisory committee meetings in 2021 (n=10), down dramatically from 35 in 2012, 29 in 2018. Nonetheless the FDA did approve 50 new drugs (NDA) in 2021. https://t.co/rSzHkIMEfg
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Patients on biologics are NOT at higher risk for COVID-19 infx. Retrospective matched cohort study compared 7631 Biologic Rx pts to 74910 matched cohort with equal Infx & death rates. COVID infx assoc w/ age, minorities, more comorbidities https://t.co/GxmgWIbgSo
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Duloxetine added to usual analgesics failed to improve pain in 132 hip or knee OA pts by WOMAC pain scores: 1) Dulox + usual care vs 2) Usual care showed no diff in pain at 3 mos or 12 mos. https://t.co/9gR2PNVrPl
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Good (long) open read review of Imaging in NPSLE (CNS lupus); mainly showing there is no SPECIFIC CNS imaging finding for NPSLE. Rather imaging (CT, MRI) done to r/o other pathology. PRES, PML, Vasculopathy, White matter lesions https://t.co/baUp6kjsKr
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
Study of subcutaneous ianalumab in patients with primary Sjögren's syndrome met primary objective, showing dose-related decrease in disease activity (ESSDAI) at week 24: randomised, double-blind, placebo-controlled trial. https://t.co/NqdDWqpX2g https://t.co/PSxSRx28fM
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The Lancet @TheLancet ( View Tweet )
4 years 6 months ago
My patient measures morning stiffness in his joints by coffee units. Today, it’s 3 ☕️- an equivalent of 1 hour. #rheumatology
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 6 months ago
In Mouse Model of Lupus, when the gut microbiome of NZM2410 mice colonized w/ SFB, glomerulonephritis worsened & was assoc. w/ incr in TH17, MCP-1 and CXCL1, & more microbial abundance & biodiversity (dysbiosis) https://t.co/bLxrJZKTDZ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 6 months ago
