#ACR21 2022 ACR/EULAR MPA Criteria ▶️Classification, NOT diagnostic! ⭐️Clinical: negative for nasal GPA symptoms ⭐️Lab: +6 for pANCA or MPO, negative for cANCA/PR3 or eosinophilia @RheumNow https://t.co/6YWmabNzuH https://t.co/XVzBF2KONp

Elevated CRP levels (>3) in PsA associated with ⬆️risk of cardiovascular events ⭐️NSAID use significantly REDUCED risk of CV events Abs#1920 #ACR21 @RheumNow https://t.co/gIz9f4SlWo https://t.co/V4uDeO3Iuz

Racial differences in PsA patients in large US real world database 95% Whites (W) and 5% were AA NSAIDs: 80% W and 78% AAs TNFI: 51% W and 41% of AAs DMARDs: 72% of W and 98% of AAs HTN/DM/Obesity/Gout 🔼 AA Cancer/osteoporosis /anxiety 🔼 whites Abst#1780 #ACR21 @Rheumnow https://t.co/7ee4bVU7ZA

Another study linking long term GC and CV risk in RA! Medicare data >65yo 130000+ pts 1-year incidence CV ⬆️ as follows: 📍Dose ≤5mg 1.4% 📍Dose 5-10mg 1.7% 📍Dose >10mg 1.9% Not replicated in younger pts (Optum data) #ACR21 #Abst1915 @RheumNow https://t.co/DLXdfvfiBW

#ACR21 2022 ACR/EULAR EGPA Criteria ▶️Classification, NOT diagnostic! ⭐️Clinical: obstructive airway, polyps, MM ⭐️Labs: eosinophilia & extravasc eos-inflamm bx, negative points for Hematuria, cANCA or PR3 - Least sensitive: 85%, but 99% specific @RheumNow https://t.co/6YWmabNzuH https://t.co/kLVqXzNTEf

#ACR21 #Abstr1908 Potential prognostic biomarker for lymphoma in #sjogren. ISG15 (IFN-I) expression was consistently ⬆️in pts with lymphoma vs none, both in blood and salivary gland biopsy. Work needed re: relation to other markers, ethnicity @RheumNow https://t.co/8VYYEXpXSw https://t.co/ZIkpx5kUfu

Abst 1916 England & colleagues determined if anti-MAA Ab = predictor of incident RA-ILD - Anti-MAA Ab significantly associated w/ incident RA-ILD - Strongly associated w/ higher concentrations anti-MAA - Antibody associations = antigen/isotype dependent #ACR21 @RheumNow https://t.co/z1RspmxBvc https://t.co/hvUm4O6RmX

DAS-28 independently associated survival in RA-ILD. As I keep saying, treating the rheumatoid disease properly is the current best strategy for treating RA-ILD. Abstr#1918 #ACR21 @RheumNow #ACRBest https://t.co/FpUK6upyOi

@Will_I_Am_Osler @zach_wallace_md @RheumNow Very nice, amazingly similar! - also 3/4 with IgG4 >5xULN - similar list of other diseases wonderful to have correlation over multiple continents, the beauty of an international meeting like #ACR21! https://t.co/vabBKNbd7u

Machine learning algorithm demonstrated high level of accuracy (88%) and precision (0.95) in diagnosing potential cases of axSpA ⭐️Is there a role for ML to facilitate faster rheum eval for suspicious axSpA cases? Abs#1922 #ACR21 @RheumNow https://t.co/tAPfROPICU https://t.co/HJD37B9jZw