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2025 BSR Recommendations for ANCA-associated Vasculitis The BSR and BHPR have published a guideline for the management of adults with AAV; specifically three conditions: GPA, MPA, and EGPA. https://t.co/nYpbBK7Ahr https://t.co/XcfL4KRHlj
Dr. John Cush @RheumNow ( View Tweet )
5 months 1 week ago
Novartis announced top line results of its ianalumab (VAY736;B cell inhibitor) in primary Sjögren’s dz. 2 RCTs, NEPTUNUS-1 and NEPTUNUS-2, met met primary endpoints w/ statistically significant improvements in disease activity in Sjögren’s patients. https://t.co/cIBhF3YJh3 https://t.co/YRTq6LEFhm
Dr. John Cush @RheumNow ( View Tweet )
5 months 1 week ago
Rheums Speak - RA Treatment Survey RheumNow's August 2025 “Live Vote” surveys will examine Rheumatologist impressions, knowledge and practices over the last 20 years when treating rheumatoid arthritis. https://t.co/hJSQ5mMJ6b https://t.co/7sBXpzkVLg
Dr. John Cush @RheumNow ( View Tweet )
5 months 1 week ago
Aging Quiets Lupus UCSF researchers have found that epigentic changes in interferon genes over time may lead to lupus being less active as they age. https://t.co/MLBFLXnXOQ https://t.co/9aacdZPoED
Dr. John Cush @RheumNow ( View Tweet )
5 months 1 week ago
"What you do makes a difference, and you have to decide what kind of difference you want to make." – Jane Goodall

Dr. John Cush @RheumNow ( View Tweet )

5 months 1 week ago
Full read review of DMARD effects on CV Risks. Strongest CV protective effects for MTX & TNF inhibitors. Potentially beneficial are sulfasalazine, hydroxychloroquine, & leflunomide. More info needed on IL-6, IL-17/23 inhibitors. Concerns over NSAIDs & JAKi https://t.co/0BW4StS15N
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
Large metanalysis of TNFi use in immune-mediated inflammatory diseases (45 studies, 150K pts) shows no increased risk of de novo heart failure (HF), and no significant risk of HF worsening w/ TNFis. https://t.co/9sRVsMZ1kv https://t.co/igCdcQMVK3
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
FDA Approves Vagal Nerve Stimulator for RA SetPoint Medical announced the FDA approved the SetPoint System, a neuroimmune modulation treatment for moderate-to-severe rheumatoid arthritis (RA), for patients not well-managed or cannot tolerate—existing RA therapies like https://t.co/MtVny1iBQ4
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
Smoking and the Global Burden of Rheumatoid Arthritis Detailed analysis of the Global Burden of Disease (GBD) 2021 database shows that tobacco and smoking is one of the most significant environmental risk factors for RA over the last 20 years. https://t.co/4IDf1ZTl7w https://t.co/oM0bNXIw28
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
RA leads to ILD: but ILD does not lead to RA New research sheds light on the link between rheumatoid arthritis (RA) and idiopathic pulmonary fibrosis (IPF). A team from Taizhou Hospital used advanced multi-omics methods to explore the causal relationship between these two https://t.co/QbY6GC0KBZ
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
Juvenile Idiopathic Arthritis - NEJM Review Sandborg et al. has published an overview of juvenile idiopathic arthritis (JIA) - its classification, biology, genetics, , clinical presentations and treatment advances in the New England Journal of Medicine (NEJM). https://t.co/ykI9zAUXaF
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
DID YOU KNOW? >30% of Systemic Sclerosis pts present without Raynauds!. Data from 2 large US cohorts, of SSc dx with puffy fingers/hands or other symptoms. Such patients presented with more severe skin and musculoskeletal disease. https://t.co/NP3KeUL5iX https://t.co/XWiAIljujL
Dr. John Cush @RheumNow ( View Tweet )
5 months 2 weeks ago
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