Tweets
Post hoc analysis of pooled data from 19 clin trials on SEC & CV risk & systemic #inflammation in PsO, PsA, AS
📌Traditional CV parameters remained stable on all SEC treated grps
📌SEC sig. ⬇hsCRP & NLR
@RheumNow #ACR21 abs1835 https://t.co/iCaGFbXNXn
sheila @RHEUMarampa ( View Tweet )
4 years 8 months ago
French study shows more than 75% of RA/SpA pregnancies resulted in a live-birth, BUT 50% of pts had at least one unfavorable pregnancy outcome! However, miscarriage prevalence lower than in reported literature. Abs 1724 #ACR21 #RheumNow @RheumNow https://t.co/64PspIKPTu https://t.co/LyfHVARAgd
Dr. Rachel Tate @uptoTate ( View Tweet )
4 years 8 months ago
IVIG can passively transfer donor Ab including 'clinically significant' e.g. HBcAb
@OchsnerHospMed 123 pts HBcAb+ post-IVIG
37 had HBcAb- captured pre-IVIG
of those, 22 received prob unnecessary antiviral Rx
Be smart: pre-IVIG, anticipate - test HBV
#ACR21 ABST1528 @RheumNow
David Liew @drdavidliew ( View Tweet )
4 years 8 months ago
2 year study shows low rates of radiographic progression in PsA pts on guselkumab
#ACR21 @RheumNow Abs#1805
https://t.co/dobg3cEXXG https://t.co/m1P24qPAhy
Links:
Robert B Chao, MD @doctorRBC ( View Tweet )
4 years 8 months ago
SERENA interim analysis on interruption of secukinumab in AS and PsA
🔹>=16 wks of Rx before interruption of >= 3 mo.
🔹75-80% of pts reinitiated w/o loading phase
🔹AS: BASDAI, PGA stable
🔹PsA: SJC, TJC returned to Rx baseline
https://t.co/3G6rVW8TPv
#ACR21 Abst#1361 @RheumNow
Pedro Castillo @_Castillo_Pedro ( View Tweet )
4 years 8 months ago
Have you heard of pSpA? (Peripheral) pSpA: distinct clinical phenotype w/ intermediate features between pure PsA & pure axSpA but w/ a higher disease burden compared to both diseases, & lower use of b-DMARDs. Abs 1787 #ACR21 #ACRbest #RheumNow @RheumNow https://t.co/Wsysm7A0Y3 https://t.co/rwQ8ukBEDq
Dr. Rachel Tate @uptoTate ( View Tweet )
4 years 8 months ago
Genes for oral aphthous ulcers common in gen pop’n, Behcets and w auto inflammatory PFAPA - kids w fevers ⬆️IL12 Kastner practical gene stories @RheumNow #ACR21 9T119. Have a listen. Bench to bedside & back https://t.co/UkPzoYbBNb
Janet Pope @Janetbirdope ( View Tweet )
4 years 8 months ago
ARIAA Study - Abatacept Reverses ACPA+ Subclinical Arthritis: Dr. Jack Cush discusses abstract #0455, a preclinical RA intervention trial - abatacept or placebo given to at risk individuals (arthralgias, CCP+, MRI+) for 6 months, presented at #ACR21.
https://t.co/fz1hPTleMn https://t.co/V4PsPZ0ZwF
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 8 months ago
5 yr multinational PROOF study - enrolled 1612 axSpA pts enrolled (65% xray+ axSpA; 35% nr-axSpA) nraxSpA had more enthesitis, PSO IBD. Over time, more TNFi use (less NSAIDs) w/ less disease activity #ACR21 Abst #0363 https://t.co/5DdDlCjq9h (Graph: NSAID use over time) https://t.co/5JE69vTIy9
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 8 months ago
Quick plug:
not all joint pain in ICI-treated pts needs reflex steroids
eg OA can get exacerbated by ICI Rx
(ICI-aOA)
call rheum, hold the PNL & save tumor response
@ReidMDMPH @got_rheum @lovetolearn27 +me
#ACR21 ABST1518 @RheumNow
our paper @jitcancer https://t.co/InespbOn6m https://t.co/HSjtGrwePE
David Liew @drdavidliew ( View Tweet )
4 years 8 months ago
Glory to GLORIA trial? Low dose prednisone 2mg in active RA>65yrs, N=451 All Standard care. in 2yrs, ~40% drop out- same in each grp Better RA control but NNH 9.5 w steroids, mostly non severe infections. So, prednisone debate in RA continues #ACR21 @RheumNow #ACRBest abst#1678 https://t.co/emOaYSjYAa
Janet Pope @Janetbirdope ( View Tweet )
4 years 8 months ago
Pregnant pts w/ PsA, but not AxSpA, at increased risk of pre-eclampsia. In RA pregnancies, pre-eclampsia risk increases w/ dz severity prior/during pregnancy. We need to discuss potential risks w/ pts and OB team. Abs 1722 #ACR21 #RheumNow @RheumNow https://t.co/yeQmNAZ1jV https://t.co/cBfeVKQHfr
Dr. Rachel Tate @uptoTate ( View Tweet )
4 years 8 months ago
