Avoid IFX drug holidays! In this study 400+ pts Dvlpmt of ADAs associated w/ ▶️RA vs. SPA OR 2.1 ▶️Smoking OR 1.8 ▶️Drug holidays > 11 weeks OR 4.1 ▶️High DA OR 1.5 while ◀️Concomitant IS drug OR 0.4 ◀️ IFX dose increments OR 0.4, were protective #ACR21 @RheumNow #Abst1525 https://t.co/cxx7aWX5wh

#ACR21 #Abstr1541 Any tools to help differentiate MAS vs #COVID inflammatory response? Preliminary criteria showed Sensitivity: 79.6%; Specificity: 81.3% within 6 days admission. No Triglyceride/Fibrinogen compared to 2016 ACR-EULAR & 2004 HLH @RheumNow https://t.co/c7pHaVCr5S https://t.co/6irF64qizI

#ACR21 #Abstr1876 The fact that nothing is 100% makes Medicine interesting! If you have patients who meet McAdams/Damiani criteria for relapsing polychondritis OR ICBD for Behcet, don’t forget it could be MAGIC! Anticollagen II abs may help @RheumNow https://t.co/9ZjYbWC6Td https://t.co/xbh9ahp2fh

Guselkumab 100 mg Q4W and Q8W provided robust and sustained benefits to patients with active PsA across multiple domains. Listen to my interview with Prof. Laura Coates on this and other emerging treatments in PsA here https://t.co/PSbJ0HA5a6 @RheumNow #ACR21 Abstr#1335 https://t.co/WzBOYGOxAA

Will a FDA black box warning change your JAKi practice? In May 2019, the EMA put out a warning about VTE with tofacitinib. In this French cohort, did it change the kind of pts they initiated on JAKi? no, not it did not😊 A window into the US future? #ACR21 ABST1245 @RheumNow https://t.co/QI95E1gepg

Are there people looking at steroid-sparing therapy as irAE treatment or prevention? @CCalabreseDO: are there ever #ACR21 irAE Study Group @RheumNow (also @NAbdelwahabMD @ReidMDMPH on stage) https://t.co/CLmNaLB68O

#ACR21 Abs#1536 #Vaccine uptake in people with #RheumaticDisease 👉🏼High uptake of vaccines in ~240 pts @BrighamWomens 👉🏼84% pts wanted the #COVID19 vaccine 👉🏼Physician recommendation was key determinant of uptake @RheumNow https://t.co/us0i5CW5Mi https://t.co/aLZmOPWFR3

#ACR21 #Abstr1492 Could gut microbiome contribute to Anti-Ro+/autoimmunity in #lupus? Analyses of 125 stool samples from mother of children with neonatal lupus and/or heart block revealed its potential role in genetic-environment interaction @RheumNow https://t.co/FnJtZJSCRj https://t.co/ttRdP9NIrG

Safety profile of #upadacitinib in #RA, #PsA, #AnkylosingSpondylitis 👉🏼AE rates similar across UPA, ADA & MTX in RA, and UPA & ADA in PsA 👉🏼No new safety risks with long-term use 👉🏼#Herpeszoster & incr CPK more common w/ UPA vs ADA/MTX Abs#1691 #ACR21 @RheumNow https://t.co/tKYi65kB5r

#ACR21 Abs#1677. Effects of bDMARD on Lipids: ⬆️ HDL from 62 -> 66 in 1yr (p=0.013) ❌ No signif change in LDL or LDL-C/HDL-C ratios @Rheumnow https://t.co/uMsXKwwqvW https://t.co/fhCbDoa3px