#ACR21 #Abstr0437 OK, so RTX affects #COVID vaccine but some pts need RTX. Factors predicting response to vaccine: RA vs AAV/IIM Higher IgG Longer time-to-RTX Lower RTX courses Number. Prediction Calculator is developed but need ext. validation #RheumNow https://t.co/iXSaGQ76hS https://t.co/WQAV3GRPBz

#ACR21 #Abstr0336 ANA is not a great test for #lupus diagnosis. Multianalyte Assay Panel with Cell-Bound Complement Activation Products could improve diagnosis (OR 6.3) and Drug Initiation (OR 2.8). Can we speed up implementation to clinic? #RheumNow https://t.co/jLcAtD7FaY https://t.co/YmLwmVWp6k

#ACR21 #Abstr0261 In stable Non sJIA, is it safe to taper or stop MTX? Of 375 pts in CARRA registry, 24% tapered and 14% stopped MTX. No diff in flare rates btw those continued vs tapered/stopped. Sustained remission was in ⬆️tapered vs stopped @RheumNow https://t.co/Mm1yfzRBQz https://t.co/rkHvXWj2oO

#ACR21 Ignaki Sanz makes the case that +++ AUTOANTIBODIES are integrally involved in #COVID19 immunopathogeneisis and may rise and fall w disease states- TBD what role they play in acute disease and #LongCovid @CCalabreseDO @VirusesImmunity @CleClinicMD #COVID19AB https://t.co/9dzCSh5V7R

Dr. Marvisi presented a case: refractory MPA relapsed w/prednisone < 25 mg/day. Genetic studies c/w VEXAS. Is MPA/vasculitis part of VEXAS? The experts say: Maybe- VEXAS is such a new entity, there may be a common pathway (e.g NFkB affected by ubiquination, IL-6 role) #ACR21 https://t.co/kEOsruJ8DE

She was considered a "high risk hire" b/c of her accent, being young, and being a mother of 3 children who still needs her. -Dr. Graciela Alarcon, a giant in rheumatology,talked about her life in the Global Women Leaders in Rheumatology #ACR21 @ACRheum @rheumnow #strongwomen https://t.co/Oxmy8ruIZF

Solutions to the Gender Gap: 👉treat gender equality as an innovation challenge requiring innovative solutions 👉create culture where people feel personally responsible for change (not coerced) 👉implement action plans to support behavioral changes with measurable targets #ACR21 https://t.co/BrExrHx1S7

Drs. Alarcon, Hajjaj-Hassouni, Aggarwal, and March are trailblazers for #WomeninRheum. Sage advice: "The people who open doors may be you." "Sometimes, you have to create your own opportunity." "Push your ideas, don't just watch." #ACR21 @acrheum @LauraLewMad11 moderates panel https://t.co/gxmjntDQst

Dr. P Krause (FDA/CBER Deputy Dir., Office of Vaccine Research and Review) on #COVIDvaccine in kids: 👉Children respond to vaccine better than adults; can use lower doses 👉the lower dose will mitigate safety concerns (FDA gave EUA for Pfizer vaccine for 5-11 yo) #ACR21 https://t.co/Z7kcYQKZ8S