Tweets
Abst#0858 Hopkins SLE Cohort 860 pts, 65 w/COVID19, 228 vax'd:
👉COVID19 infx did not increase dz activity, but aPLs were increased (rash decreased likely d/t quarantine and no sun exposure)
👉COVID19 vaccine did not affect dz activity #ACR21 @rheumnow
https://t.co/C65qJuMIbk
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 8 months ago
Pearls esp important for older patients #acr21:
👉🏻social isolation and or social context makes a big difference in accomplishing #goals and achieving #whatmattersmost
👉🏻encourage and motivate patients to engage someone in their community #nudge @CreakyJoints @ArthritisFdn
Una Makris @UnaMakris ( View Tweet )
4 years 9 months ago
How can behavioral therapy help people manage #ChronicIllness?
@AftonHassett mentions these at #ACR21:
- Psychiatric comorbidity
- Pain catastrophizing
- Fear avoidance
- Limited coping skills
- Poor sleep
- Physical inactivity https://t.co/1c8bThYNP0
CreakyJoints.org @CreakyJoints ( View Tweet )
4 years 9 months ago
And I’m finally in the game!! On board for #ACR21
Enjoying hearing Virginia Pascal showing data on how opsonisation of red blood cells containing mitochondria results in the induction of Type I Interferon pathways
Great paper here https://t.co/QWJLncYmC3 #ACRambassador
Chris Wincup @chriswincup ( View Tweet )
4 years 9 months ago
#ACR21 - Dr. Virginia Pascual speaking on #PrecisionMedicine in Lupus. Mitochondria in RBC's will cause more disease activity in Lupus patients. Th groups that remove Mitochondria have less disease activity. Hope this takes us to #precisionmedicine soon!. #Looms4Lupus https://t.co/sMOmeJPMJX
Looms4Lupus @Looms4Lupus ( View Tweet )
4 years 9 months ago
So fitting that @ACRheum President @DrDavidKarp has highlighted the amazing work of @rheum_covid in the #ACR21 Opening Session.
In crazy times, it delivered results with unprecedented speed, when our patients needed it most. We will look back in history with thanks.
@RheumNow https://t.co/cTnAZP9UDl
David Liew @drdavidliew ( View Tweet )
4 years 9 months ago
It's all happening for biologic therapies in PMR!
phase 2/3 double-blind RCT:
- new PMR
- n=36
- 11w PNL taper (until relapse - clinical not lab)
- weekly sc TCZ for 16w vs placebo
big benefit persists post-TCZ cessation
real steroid sparing
PMR-SPARE #ACR21 ABST0507 @RheumNow https://t.co/w8tgOPAtyJ
David Liew @drdavidliew ( View Tweet )
4 years 9 months ago
Dr B Bermas noted AAP guidelines say avoid MTX while breastfeeding, but the literature show very little MTX crosses breast milk. Dr Sammaritano stated that is true, but we don’t know how much MTX accumulates,though. #acr21 @rheumnow @UTSWRheum https://t.co/9I7HszorEO
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 9 months ago
Would you allow a pt to continue MTX while breastfeeding? #acr21 @rheumnow
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 9 months ago
Abst 0501
Kakkar & colleagues examined immunogenicity of single dose of SARS-CoV-2 Vaccine in patients with systemic sclerosis
- Vaccine is safe
- Immunosuppression lowered Ab production but no effect on T cell response
#ACR21 @RheumNow https://t.co/NsLrWHh7ZS
Akhil Sood MD @AkhilSoodMD ( View Tweet )
4 years 9 months ago
In GCA, why might you target GM-CSF over IL-6?
Entirely plausible TCZ might be leaving some Th1 stones unturned, esp:
vascular remodelling
downreg pathways
Transcriptomics from toci/mavri-treated TAB show it's plausible beyond just theory...
Cid group #ACR21 ABST0506 @RheumNow https://t.co/YephlzHOdj
David Liew @drdavidliew ( View Tweet )
4 years 9 months ago
VEXAS a new genetic disorder, (V) Vacuoles, (E) E1-enzyme, (X) X-linked, (A) Autoinflammatory, (S) Somatic. These are the important clinical features to be looking out for in clinic @RheumNow #ACR21 Session6S410 L Wilson, DO Cordona https://t.co/dBBLox6vVg
Dr. Antoni Chan @synovialjoints ( View Tweet )
4 years 9 months ago
