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Dr. Petri et al showed transition between lupus anticoagulant (-) to (+), (+) to (-), and (+) or (-) to thrombosis could be estimated by multistate Markov model. #ACR21 Abst#0076 @RheumNow https://t.co/oIvbak4lV4
Pedro Castillo @_Castillo_Pedro ( View Tweet )
4 years 9 months ago
Retrospective study of FAERS database: 186 irAE w/rheum manifestation 👉4.7% of all AEs 👉Arthritis, myositis, Sjogren, sarcoidosis were frequent 👉myositis assc w/ durvalumab, avelumab, atezolimumab and cemiplimab #ACR21 Abstr#0438 #Plenary @rheumnow https://t.co/t8UQWQicFc https://t.co/FGo6WCDQTp
TheDaoIndex @KDAO2011 ( View Tweet )
4 years 9 months ago
@BethIWallace et al. on fibromyalgianess and GC in #rheumatoidarthritis pts. Accdg to their study, pts w/⬆ levels of fibromyalgianess at BL had higher odds of GC persistence on ffup. Something to consider when evaluating need for GC adjustment. @RheumNow #ACR21 abs0120 https://t.co/MTWEXGHJ2n
4 years 9 months ago
Retrospective study of cancer pts Rx w/ ICI and autoimmune Ab (ANA, RF, CCP, SSA/SSB, ANCA) 👉152 pts 👉59% had irAE 👉preICI Ab+⬆️odds of irAE (OR 17.5 95% CI 1.76-174, p=0.015) 👉strong assc b/t +RF and +CCP for ICD-arthritis #ACR21 Abst#0440 @Rheumnow https://t.co/kUv5ddSAnY

TheDaoIndex @KDAO2011 ( View Tweet )

4 years 9 months ago
Large case-control study (n=8028) to identify baseline predictors of rheum irAEs after immune checkpoint inhibitor initiation for cancer. Type of cancer (melanoma, GU), combination ICI, pre-existing autoimmune disease, and recent GC use each had higher odds of rheum irAE #ACR21 https://t.co/rHI6VQ37QB
Jeffrey Sparks MD MMSc @jeffsparks ( View Tweet )
4 years 9 months ago
#ClinicalPearl Joint clinic btwn ophthalmology & #rheumatology helps make dx & Rx work. #ACRBest #ACR21 see work up of inflammatory eyes disease. All are allowed one acute ant uveitis- ? dogma maybe work up all. 6S117 https://t.co/Wwdv3N66HS
Janet Pope @Janetbirdope ( View Tweet )
4 years 9 months ago
#ACR21 Abst#0290: Ever wonder about other predictors of mortality in pts w/ RA-Lung Disease besides ILD (OR 2.3) or older age? ⭐︎ ↑ mortality associated w/ pleural effusions (OR 3.3) AND, notably... ⭐︎MTX use was protective (OR 0.4)!!! @RheumNow https://t.co/KKRkQVY2pf https://t.co/JsU2Rqzi6R
Meral K. El Ramahi, MD @MeralElRamahiMD ( View Tweet )
4 years 9 months ago
This study looked into the prevalence of subclinical atherosclerosis in #rheumatoidarthritis pts w/n 5 yrs of dx using carotid US. 📌vs. controls, RA pts had ⬆ CPs, cIMT ❗Screen RA pts for CV risk early on in their diagnosis @RheumNow #ACR21 abs0271 https://t.co/btU6IcM3xb
4 years 9 months ago
ASAS-PerSpA worldwide study: axSpA most common SpA from in family hx. Except in Middle Eastern/N. African pts, a FH of axSpA associated w/ +HLA-B27 in axSpA pts. PsO and IBD FH more likely -HLA-B27 . FH of ReA rare. Abs 0368 #ACR21 #RheumNow @RheumNow https://t.co/iHBccAcvLi https://t.co/FCoyVg3MGw
Dr. Rachel Tate @uptoTate ( View Tweet )
4 years 9 months ago
#ACR21 Abst#0293 RA patients with lung disease have increased rates of SSc-specific autoantibodies compared to RA w/o lung disease. ▶️ Suggests we may need to investigate further into overlap phenotype in RA-ILD @Rheumnow https://t.co/04FFuBUKmA https://t.co/A83kaie2gr
Eric Dein @ericdeinmd ( View Tweet )
4 years 9 months ago
#ClinicalPearl. ‘my eye hurts-what’s going on!’ Dr Palestine says Ophthalmologists don’t agree on uveitis naming/ethology & worse - Rheums & eye specialists don’t speak language. Need to know infections are r/o (syphillis, CXR) & if active uveitis to ⬆️Rx #ACR21 @RheumNow https://t.co/7LkhJnUKXK
Janet Pope @Janetbirdope ( View Tweet )
4 years 9 months ago
We should aim for early treatment and good retention in ax-SpA to prevent structural evolution. >12 months of TNFi treatment in the previous 2 years associated w/ ⬇️ radiographic progression of SIJ in r- and nr-axSpA in GESPIC, #Abst0174 @RheumNow #ACR21 https://t.co/2V1q4dUwFO https://t.co/lxQU4zAP1I
Aurelie Najm @AurelieRheumo ( View Tweet )
4 years 9 months ago
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