2016 ARTIC trial tested T2T w/ MTX & "bridging" tapered Prednisolone (15 mg --> 0mg over 7wks) in 237 new DMARD naive RA pts. PRED discontinuation successful in 84% @7wks, 89% @3mos, 95% @ 24 mos. Only 5% require Pred @ every visit for 2 yrs. You can D/C pred! https://t.co/O23PHq81YP

Aortitis in Giant Cell Arteritis Treated with Tocilizumab The Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group studied giant cell arteritis (GCA) with aortitis, comparing the efficacy of intravenous (IV) vs. subcutaneously (SC) tocilizumab (TCZ) - demonstrating https://t.co/GPt7sTzbpH

Retractions in Rheumatology Retractions in rheumatology are rising. An analysis of Retraction Watch data found 381 retracted articles (1989–2024), driven by misconduct or data errors. 68.5% originated in Asia, over half from China (50.7%). https://t.co/I6WmceNi2m https://t.co/6z0jHPaiaR

Notch and TGFβ Signaling in Refractory Rheumatoid Arthritis Spatial transcriptomic profiling of rheumatoid arthritis (RA) synovial biopsies (pre- and post-treatment) has revealed new insights into the pathobiology or treatment resistent RA. https://t.co/vCvFpnIOvS https://t.co/EV6OihT0br

TOPKAT Trial: Partial vs Total Knee Replacement Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little bit https://t.co/SsTXAqs4Xr

DMARD Responses in Localized Scleroderma JAMA Dermatology has published the results of a juvenile localized scleroderma (JLS) trial showing that mycophenolate mofetil (MMF) and methotrexate (MTX) are equally effective in treating JLS, noting low flare rates and possibly better https://t.co/NIR0ejs1RL

Potential New Rheumatology Drugs for 2026. These have had successful phase III RCTs and will need to be reviewed by regulators: ** deucravacitinib (Sotyktu) Tyk2 inhib for PsA ** Icotrokinra (Icotyde) oral IL-23i for psoriasis ** brepocitinib TYK2/JAK1 inhibitor for https://t.co/CQmfjIDMp3

NEJM: Aortitis Due to Large-Vessel Vasculitis 63yoM w/ Hx HTN c/o 3 mos of CP, palpitations, abdominal pain. ESR-104, CRP 85 mg/L. CT showed thickening of the thoracic & abdominal aorta. After 6wks Rx w/ AZA, HCQ, Pred, ESR/CRP still high and pt stared on SC TCZ w/ improvement. https://t.co/IWm3ZQLBUN

FDA has announced "Breakthrough Designation" for 3 drugs + 1 test being developed: ** Biogen: litifilimab (targets dendritic cells) for cutaneous lupus ** Novartis: Ianalumab (BAFF blockade) for Sjogrens ** J&J: Nipocaiimab (FcRn) for Sjogrens ** Encarta: pocket Lyme test https://t.co/zODOTWyqP8

Congratulations to Dr. Cheryl Barnabe for receiving the 2026 Distinguished Investigator Award from the Canadian Rheumatology Association, for her excellence in rheumatology research & clinical care. Dr. Barnabe is a professor at the University of Calgary https://t.co/xxNI8qR9sn https://t.co/zHkAOoyD7f

Air pollution ups ANA+: Ontariio Canadi study of 3548 serum samples (2010-13) corrlated particulate matter (PM2.5) w/ serologies. Highest vs lowest quartile PM2.5 showed higher risk of ANA ≥1:640 (OR 1.46) & ≥1:1280 (OR 1.54). Pollution has systemic immune effects! https://t.co/fJrhypNE2A