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ICYMI:
Biosimilar update: 31 FDA approved biosimilars, but only 60% made it to market. 2015 to 2019, drug spending grew 6.1%, biologic spending grew 14.6%; biologics are 43% of US drug spending. Most biologics at ~30% discount. https://t.co/4paYH8hkUi https://t.co/Ztjp9g3uo3
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
In case you missed it:
Patients with rheumatoid arthritis (RA) who had a history of cancer did NOT have an increased risk of new or recurrent cancers if treated with biologic therapies, a meta-analysis found. #RheumNow
https://t.co/jM9oiRin2M https://t.co/RknVHmZK98
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
New podcast available for download! “Jack of All Subspecialties”—find wherever you get your podcasts.
https://t.co/UvQRiLOWsr https://t.co/oUqrhXjSJJ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
CDC Advises COVID-19 Vaccines for Pregnant Women
https://t.co/cRQx8QdO7F
#RheumNow https://t.co/iL6JIEiGFw
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Using EHR data from the UK, the frequency of children and young people with JIA in 2018 was studied. Age standardised incidence rate =5.61 per 100 000; prevalence rate=43.5 per 100 000. 5-yr incidence rates did not change over time. https://t.co/mwmf5nktkF
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
A placebo controlled RCT of canakinumab in 31 Adult Stills pts with arthritis showed responders (by DAS28) had signif reductions in calprotectin, IL-1RA, IL-18, IL-at wk 4. Unfortunately: didnt look at fever, rash, serositis, etc. https://t.co/p4Fohos2iU
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
JAK inhibitors as potential treatment for Juvenile Dermatomyositis: nice review of the biology of JAKi effects and the reports of JAKi success in adults and kids with IIM https://t.co/k3qunsCdBN
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Early Diastolic Dysfunction in Premenopausal Women with RA
https://t.co/2pyzT20RCF https://t.co/8viSUbpywX
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Can I get the INFLUENZA and COVID Vaccines together? The CDC says: "YES...both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine.... ideally get a flu vaccine by the end of October." https://t.co/T49zm6kWGE https://t.co/DxL9rT2UqJ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
A population based Swedish study of birth records shows that antibiotic exposure in first three years of life to be associated with a future risk of JIA, although infections during fetal life or childhood did not increase risk of JIA. #RheumNow
https://t.co/aXFOxoOyF1 https://t.co/Md0zBm5Txl
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
SENSCIS trial compared 1 yr of nintedanib (NIN) vs placebo in 576 SSc-ILD pts. NIN was more effective (less FVC decline) in 1) α-topoisomerase Ab neg (57.2 vs 30 ATA+), 2) mRSS ≥18 (88.7 vs 26 mRSS<18), & 3) diffuse (57 vs local 25) SSc pts https://t.co/cLuTBDeJD6
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Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Alendronate may protect against type 2 Diabetes. Data from National Danish Patient Registry, presented at the EASD meeting compared 160k T2DM & 500k controls, T2DM following alendronate adjusted OR=0.64; 0.62-0.66); >8yrs OR=0.47 https://t.co/RYEZodUZtv
Links:
Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
