Tweets
Comparing COVID vaccines in rheum dz pts - 45 took J&J vax compared to 994 on mRNA vaccines. Detectable Ab responses lower w/ J&J (80% vs 92%, p=0.03) than mRNA vax. RTX, MMF & steroids significantly depressed Ab responses https://t.co/6ZJU8EVF5n
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
Arthritis clinic referrals divided into 2 cohorts: (A) 163 w/ MSK US before visit; (B) 109 without initial MSK US. MSK-US at 1st visit reduced time to Dx from mean 31 to 12 days (p< 0.01), # of clinic visits, & increased odds of inflamm Dx (47% vs 27%) https://t.co/FaXLBlRlxy
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
MTX impairs COVID Vax responses in IMID pts from Ehrlangen & NYU. BNT162b2 mRNA COVID-19 vaccination in rheumatic pts (82) & 206 controls. Adequate immunogenicity seen in IMID & TNFi Rx >90%, but less (50-72%) w/ MTX (45) https://t.co/EvxZSAD6ve
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
#ClinicalPearl My pt’s rheumatoid nodules ⬇️ when she continued off her #methotrexate post #CovidVaccine. She restarted her JAKi + #plaquenil https://t.co/FqNX9k7FUN
Janet Pope @Janetbirdope ( View Tweet )
4 years 11 months ago
Why do they always say larger RCTs are needed? RCT was >1000 and superiority of Bimekizumab to Secukinumab was shown. Maybe it is better to inhibit more than IL17A with added value of IL17F @RheumNow https://t.co/DAwZKxxinM
Janet Pope @Janetbirdope ( View Tweet )
4 years 11 months ago
In the land of a surfeit of free vaccines, this is the dark day when we crossed the line of over 100,000 hospitalizations, more than 25,000 patients in the ICU (highest for the pandemic), over 1300 deaths, and over 186,000 new cases. https://t.co/A8KNIClCwX
Eric Topol @EricTopol ( View Tweet )
4 years 11 months ago
Cognitive impairment (CI) is not a consequence of having rheumatoid arthritis (OR = 1.12, 0.80–1.58). Population survey study of 4262 adults >50 yrs. 63% of RA had normal cognition , 25% w/ CI, 12% dementia (similar to non-RA- 66%, 22%, 12%) https://t.co/7RFOk8Nrkm
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
A current report in Arthritis & Rheumatology examined the Nurses Health Study II data set and shows that parental smoking, and passive exposure to children, can later lead to an increased risk of adult-onset incident seropositive RA.
https://t.co/szl5L7DGJG https://t.co/ScV51iJsA9
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
European Commission approves upadacitinib (Rinvoq)-first JAK Inhibitor for use in adults & adolescents with Moderate to Severe Atopic Dermatitis. UPA is approved for atopic dermatitis in other nations, Russia, Saudi Arabia; pending review in US https://t.co/hiPkJoJCex
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
Rheumatic Events With Checkpoint Inhibitors: Tumor Type Matters
https://t.co/vT6185ycoG https://t.co/ImEejSrOPW
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
Given the DELTA breakthrough surge how do you feel about live medical meetings (n> 50) in the next 6 weeks
@Janetbirdope @KDAO2011 @psufka @AngusWorthing @RonanTKavanagh @RheumNow @MattieRheumMD @rheum_cat @jeffsparks @hausmannMD @CCalabreseDO @DrSwamyV
Leonard Calabrese @LCalabreseDO ( View Tweet )
4 years 11 months ago
Among pregnant women, receipt of the BNT162b2 vaccine was associated with a 78% lower risk of incident SARS-CoV-2 infection. Cohort study tincluded 15 060 pregnant women in Israel. No adverse pregnancy outcome difference in Vax Pts https://t.co/jXUjaKIfUV
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Dr. John Cush @RheumNow ( View Tweet )
4 years 11 months ago
