Tweets
New GRAPPA 2021 PsO and PsA Treatment Recommendations by Dr. Rachel Tate ( @uptoTate )
The evidence-based recommendations from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis were presented at #EULAR2021.
Read more.
https://t.co/AnHQGA8aKs https://t.co/yJbymc9csR
Links:
Dr. John Cush @RheumNow ( View Tweet )
5 years 2 months ago
Caveats:
-secondary analysis (consider exploratory)
-unclear clinical significance (modest ΔeGFR)
-baseline CrCl 40+ (do NOT use in advanced CKD)
-systemic rheumatic diseases excluded (unethical to randomize to PBO for 2 years)
-generalizability (all had CVD, M>F, mean age 66)
Jeffrey Sparks MD MMSc @jeffsparks ( View Tweet )
5 years 2 months ago
Results: MTX vs. PBO
✅Difference in least-squares mean ΔeGFR 0.93 mL/min/1.73m2 (p<0.001)
✅HR for kidney AE on safety labs: 0.73 (0.59-0.91)
✔️HR for kidney AE clinical events: 0.87 (0.56-1.36)
✔️4 vs. 8 severe kidney AEs (HR 0.50, 0.15-1.64)
Jeffrey Sparks MD MMSc @jeffsparks ( View Tweet )
5 years 2 months ago
Unmet need to sort Undifferentiated connective tissue disease (UCTD; ANA+ve + =>1 criteria) as it impacts #psychosocial. Dr Siegel reported UCTD impaired #HRQoL and ⬆️anxiety, depression and fatigue. More works needed and to compare with #SLE and HC #EULAR2021 #POS0715 @RheumNow https://t.co/2elkeFmWwC
Md Yuzaiful Md Yusof @Yuz6Yusof ( View Tweet )
5 years 2 months ago
We need to revisit #SLEDAI #lupus arthritis. Drs Mahmoud & Vital reported only 48% without swelling had MSK-US synovitis; 90% with swelling. They proposed new TERM: Inflammatory joint pain with =>2 SJC. Need to get this right as it impacts SRI-4 #EULAR2021 #POS0746 @RheumNow https://t.co/JPqOMLQ2ES
Md Yuzaiful Md Yusof @Yuz6Yusof ( View Tweet )
5 years 2 months ago
Very true. He pushes you to excellence. https://t.co/NTzrmHeGKD
k dao @KDAO2011 ( View Tweet )
5 years 2 months ago
SLE Molecular Phenotype for Personalized Medicine: Drs. Yusof and Garantziotis #EULAR2021
https://t.co/HJzyXBJ0fZ https://t.co/06jvGcczmi
Links:
Dr. John Cush @RheumNow ( View Tweet )
5 years 2 months ago
Would it help to record #SLE BILAG-2004 index in your busy clinic if this was made easy? Dr Carter reformatted EASY-BILAG with colour-coding and in-built glossary. Most assessment can be done in 1 page!This tool boosts accuracy, speed & usability #EULAR2021 #POS0748 @RheumNow https://t.co/v27rrK0ob3
Md Yuzaiful Md Yusof @Yuz6Yusof ( View Tweet )
5 years 2 months ago
HUR-BIO real life data, PsA pts started bDMARDs w/in 18 mo of dx vs almost 3x later in RA pts (tended to remain on csDMARDs.) This distinction may be explained by synthetic DMARDs on activity differences between the RA & PsA. Abstract #POS0633 #EULAR2021 https://t.co/VkkF28jm2f https://t.co/IkfGdZYNY3
Links:
Dr. Rachel Tate @uptoTate ( View Tweet )
5 years 2 months ago
@alberta_hoi @earlyarthritis @RheumNow Indeed. The #EULAR2021 session on this is one I have to go back and watch! https://t.co/0kLLQVbyWl
David Liew @drdavidliew ( View Tweet )
5 years 2 months ago
Reassuring safety data from @rheum_covid COVAX registry on #COVID #vaccination in patients with #RMDs
👉🏼Vaccine welltolerated by most patients
👉🏼Most adverse events similar to gen population
👉🏼RMD flares were rare after vaccine
👉🏼#GetVaccinated!
LB0002 @pedrommcmachado #EULAR2021 https://t.co/bheIcVZ9xa
Mrinalini Dey @DrMiniDey ( View Tweet )
5 years 2 months ago
🤜MTX safe from kidney perspective if baseline CrCl 40+
🤜Potential for immunomodulation to prevent/slow progression to CKD? Deserves dedicated studies @Nephro_Sparks
Jeffrey Sparks MD MMSc @jeffsparks ( View Tweet )
5 years 2 months ago
